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pubmed-article:16403184pubmed:abstractTextStudies have reported decreased N-acetylaspartate (NAA) in dorsolateral prefrontal cortex (DLPFC) of adults and children with bipolar disorder (BD), suggesting decreased neuronal density in this area. However, it is unclear if this finding represents neurodegeneration after or a trait marker present before BD onset. To address this question, we used proton magnetic resonance spectroscopy ((1)H-MRS) to compare DLPFC levels of NAA among bipolar offspring with early-onset BD, bipolar offspring with subsyndromal symptoms of BD and healthy children.lld:pubmed
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pubmed-article:16403184pubmed:articleTitleN-acetylaspartate levels in bipolar offspring with and at high-risk for bipolar disorder.lld:pubmed
pubmed-article:16403184pubmed:affiliationDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA.lld:pubmed
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