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pubmed-article:16394557pubmed:dateCreated2006-1-5lld:pubmed
pubmed-article:16394557pubmed:abstractTextAs one of approaches of developing novel HPLC stationary phases, we prepared Cu-octabromotetrakis(4-carboxyphenyl)porphine derivative-immobilized silica gels (Cu-OBTCPP(D)), and evaluated the availability of the resultant Cu-OBTCPP(D) as a stationary phase for separation of poly-aromatic-hydrocarbons (PAHs) and their related compounds. A Cu-OBTCPP(D) column was revealed to have an ability to separate simple PAHs and be useful as a stationary phase in both polar and non-polar eluents. The retention property of the Cu-OBTCPP(D) column was evaluated in various comparative experiments using commercially available columns. In comparison with 2-(1-pyrenyl)ethyl dimetylsilyl silica gel column (PYE column) regarding the retention behavior for PAHs etc., the Cu-OBTCPP(D) column showed stronger interactions involving pi electron in non-polar eluent than PYE column. In comparison with a pentabromobenzyloxy propylsilyl silica gel column (PBB column) regarding the influence of bromination, the Cu-OBTCPP(D) column was affected differently from the PBB column. In comparison with nitrophenylethyl silica gel column (NPE column) regarding the retention behavior for compounds having a dipole in a non-polar eluent, the Cu-OBTCPP(D) column showed electrostatic interactions such as dipole-dipole interaction equivalent to or larger than the NPE column.lld:pubmed
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pubmed-article:16394557pubmed:authorpubmed-author:HaginakaJunJlld:pubmed
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pubmed-article:16394557pubmed:authorpubmed-author:MifuneMasakiMlld:pubmed
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pubmed-article:16394557pubmed:authorpubmed-author:TsukamotoIkuk...lld:pubmed
pubmed-article:16394557pubmed:authorpubmed-author:TanakaKurumiKlld:pubmed
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pubmed-article:16394557pubmed:pagination94-8lld:pubmed
pubmed-article:16394557pubmed:dateRevised2010-11-18lld:pubmed
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pubmed-article:16394557pubmed:year2006lld:pubmed
pubmed-article:16394557pubmed:articleTitleHPLC retention behaviors of poly-aromatic-hydrocarbones on Cu(II)-octabromotetrakis(4-carboxyphenyl)porphine derivatives-immobilized aminopropyl silica gels in polar and non-polar eluents.lld:pubmed
pubmed-article:16394557pubmed:affiliationDepartment of Pharmaceutical Sciences, Graduate School of Medicine and Dentistry and Pharmaceutical Sciences, Okayama University, Tsushima-Naka, Japan. mifune@pharm.okayama-u.ac.jplld:pubmed
pubmed-article:16394557pubmed:publicationTypeJournal Articlelld:pubmed