pubmed-article:16392789 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:16392789 | lifeskim:mentions | umls-concept:C0087111 | lld:lifeskim |
pubmed-article:16392789 | lifeskim:mentions | umls-concept:C0226896 | lld:lifeskim |
pubmed-article:16392789 | lifeskim:mentions | umls-concept:C0205531 | lld:lifeskim |
pubmed-article:16392789 | lifeskim:mentions | umls-concept:C0442027 | lld:lifeskim |
pubmed-article:16392789 | lifeskim:mentions | umls-concept:C0034289 | lld:lifeskim |
pubmed-article:16392789 | lifeskim:mentions | umls-concept:C1527415 | lld:lifeskim |
pubmed-article:16392789 | lifeskim:mentions | umls-concept:C0243192 | lld:lifeskim |
pubmed-article:16392789 | lifeskim:mentions | umls-concept:C0003469 | lld:lifeskim |
pubmed-article:16392789 | lifeskim:mentions | umls-concept:C0016904 | lld:lifeskim |
pubmed-article:16392789 | lifeskim:mentions | umls-concept:C0005456 | lld:lifeskim |
pubmed-article:16392789 | lifeskim:mentions | umls-concept:C0935763 | lld:lifeskim |
pubmed-article:16392789 | lifeskim:mentions | umls-concept:C1879648 | lld:lifeskim |
pubmed-article:16392789 | pubmed:issue | 1 | lld:pubmed |
pubmed-article:16392789 | pubmed:dateCreated | 2006-1-5 | lld:pubmed |
pubmed-article:16392789 | pubmed:abstractText | A series of high-affinity GABA(A) agonists with good oral bioavailability in rat and dog and functional selectivity for the GABA(A)alpha2 and -alpha3 subtypes is reported. The 7-trifluoromethylimidazopyrimidine 14g and the 7-propan-2-olimidazopyrimidine 14k are anxiolytic in both conditioned and unconditioned animal models of anxiety with minimal sedation observed at full BZ binding site occupancy. | lld:pubmed |
pubmed-article:16392789 | pubmed:language | eng | lld:pubmed |
pubmed-article:16392789 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16392789 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:16392789 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16392789 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16392789 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16392789 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16392789 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16392789 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:16392789 | pubmed:month | Jan | lld:pubmed |
pubmed-article:16392789 | pubmed:issn | 0022-2623 | lld:pubmed |
pubmed-article:16392789 | pubmed:author | pubmed-author:WaffordKeith... | lld:pubmed |
pubmed-article:16392789 | pubmed:author | pubmed-author:AtackJohn RJR | lld:pubmed |
pubmed-article:16392789 | pubmed:author | pubmed-author:PikeAndrewA | lld:pubmed |
pubmed-article:16392789 | pubmed:author | pubmed-author:SohalBindiB | lld:pubmed |
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pubmed-article:16392789 | pubmed:author | pubmed-author:OwensAndrew... | lld:pubmed |
pubmed-article:16392789 | pubmed:author | pubmed-author:KellySarahS | lld:pubmed |
pubmed-article:16392789 | pubmed:author | pubmed-author:StanleyJoanna... | lld:pubmed |
pubmed-article:16392789 | pubmed:author | pubmed-author:MarshallGeorg... | lld:pubmed |
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pubmed-article:16392789 | pubmed:author | pubmed-author:CookSusan MSM | lld:pubmed |
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pubmed-article:16392789 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:16392789 | pubmed:day | 12 | lld:pubmed |
pubmed-article:16392789 | pubmed:volume | 49 | lld:pubmed |
pubmed-article:16392789 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:16392789 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:16392789 | pubmed:pagination | 35-8 | lld:pubmed |
pubmed-article:16392789 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
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pubmed-article:16392789 | pubmed:year | 2006 | lld:pubmed |
pubmed-article:16392789 | pubmed:articleTitle | Imidazo[1,2-a]pyrimidines as functionally selective and orally bioavailable GABA(A)alpha2/alpha3 binding site agonists for the treatment of anxiety disorders. | lld:pubmed |
pubmed-article:16392789 | pubmed:affiliation | Department of Medicinal Chemistry, Merck Sharp Laboratory, Neuroscience Research Centre, Terlings Park, Eastwick Road, Harlow, Essex, UK. | lld:pubmed |
pubmed-article:16392789 | pubmed:publicationType | Journal Article | lld:pubmed |
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