| pubmed-article:16362284 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16362284 | lifeskim:mentions | umls-concept:C0011860 | lld:lifeskim |
| pubmed-article:16362284 | lifeskim:mentions | umls-concept:C0026336 | lld:lifeskim |
| pubmed-article:16362284 | lifeskim:mentions | umls-concept:C0015127 | lld:lifeskim |
| pubmed-article:16362284 | lifeskim:mentions | umls-concept:C0577559 | lld:lifeskim |
| pubmed-article:16362284 | lifeskim:mentions | umls-concept:C1314792 | lld:lifeskim |
| pubmed-article:16362284 | lifeskim:mentions | umls-concept:C0021655 | lld:lifeskim |
| pubmed-article:16362284 | lifeskim:mentions | umls-concept:C0205217 | lld:lifeskim |
| pubmed-article:16362284 | lifeskim:mentions | umls-concept:C1256369 | lld:lifeskim |
| pubmed-article:16362284 | lifeskim:mentions | umls-concept:C0591833 | lld:lifeskim |
| pubmed-article:16362284 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:16362284 | pubmed:dateCreated | 2006-2-8 | lld:pubmed |
| pubmed-article:16362284 | pubmed:abstractText | Although insulin resistance induces compensatory increases in beta cell mass and function to maintain normoglycaemia, it is not clear whether insulin resistance can precipitate beta cell dysfunction and hyperglycaemia without a pre-existing beta cell susceptibility. We therefore examined the beta cell phenotype in the MKR mouse, a model in which expression of a dominant-negative IGF 1 receptor (IGF1R) in skeletal muscle leads to systemic insulin resistance and diabetes. | lld:pubmed |
| pubmed-article:16362284 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16362284 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16362284 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16362284 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:16362284 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16362284 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:16362284 | pubmed:issn | 0012-186X | lld:pubmed |
| pubmed-article:16362284 | pubmed:author | pubmed-author:WheelerM BMB | lld:pubmed |
| pubmed-article:16362284 | pubmed:author | pubmed-author:LeroithDD | lld:pubmed |
| pubmed-article:16362284 | pubmed:author | pubmed-author:ChaiYY | lld:pubmed |
| pubmed-article:16362284 | pubmed:author | pubmed-author:YaiHH | lld:pubmed |
| pubmed-article:16362284 | pubmed:author | pubmed-author:ChanC BCB | lld:pubmed |
| pubmed-article:16362284 | pubmed:author | pubmed-author:AsgharZZ | lld:pubmed |
| pubmed-article:16362284 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16362284 | pubmed:volume | 49 | lld:pubmed |
| pubmed-article:16362284 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16362284 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16362284 | pubmed:pagination | 90-9 | lld:pubmed |
| pubmed-article:16362284 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
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| pubmed-article:16362284 | pubmed:meshHeading | pubmed-meshheading:16362284... | lld:pubmed |
| pubmed-article:16362284 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:16362284 | pubmed:articleTitle | Insulin resistance causes increased beta-cell mass but defective glucose-stimulated insulin secretion in a murine model of type 2 diabetes. | lld:pubmed |
| pubmed-article:16362284 | pubmed:affiliation | Department of Physiology, University of Toronto, 1 King's College Circle Room 3352, Toronto, ON, Canada. | lld:pubmed |
| pubmed-article:16362284 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16362284 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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