Linked Life Data

16361550

Source:http://linkedlifedata.com/resource/pubmed/id/16361550

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SubjectPredicateObjectContext
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pubmed-article:16361550pubmed:issue24 Pt 1lld:pubmed
pubmed-article:16361550pubmed:dateCreated2005-12-19lld:pubmed
pubmed-article:16361550pubmed:abstractTextThe Dukes stage is used to stratify colorectal cancer patients into groups of different prognosis and need of adjuvant radiotherapy and chemotherapy. However, approximately 80% of patients with Dukes stage C colorectal cancer receive cytotoxic therapy without any expected benefit, for such patients would either not relapse without adjuvant therapy or they would inevitably do so because of tumor resistance to the available regimens. On the other hand, as 20% of Dukes stage B patients would relapse after surgery, adjuvant therapy could improve their survival. Improvement of the Dukes stage predictive accuracy is necessary to better assign patients for adjuvant therapies, especially nowadays when antiangiogenic agents are being incorporated in the clinical practice.lld:pubmed
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pubmed-article:16361550pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:16361550pubmed:year2005lld:pubmed
pubmed-article:16361550pubmed:articleTitleInclusion of vasculature-related variables in the Dukes staging system of colon cancer.lld:pubmed
pubmed-article:16361550pubmed:affiliationDepartment of Pathology, Democritus University of Thrace, Alexandroupolis, Greece, and Department of Pathology, John Radcliffe Hospital, UK. targ@her.forthnet.grlld:pubmed
pubmed-article:16361550pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:16361550pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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