| pubmed-article:16323831 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16323831 | lifeskim:mentions | umls-concept:C0220806 | lld:lifeskim |
| pubmed-article:16323831 | lifeskim:mentions | umls-concept:C0036002 | lld:lifeskim |
| pubmed-article:16323831 | lifeskim:mentions | umls-concept:C0039848 | lld:lifeskim |
| pubmed-article:16323831 | lifeskim:mentions | umls-concept:C0205681 | lld:lifeskim |
| pubmed-article:16323831 | lifeskim:mentions | umls-concept:C1512693 | lld:lifeskim |
| pubmed-article:16323831 | pubmed:issue | 25 | lld:pubmed |
| pubmed-article:16323831 | pubmed:dateCreated | 2005-12-5 | lld:pubmed |
| pubmed-article:16323831 | pubmed:abstractText | [structure: see text] Molecular clips functionalized by phosphonate or phosphate groups bind thiamine diphosphate (TPP) and S-adenosylmethionine (SAM) with high affinity in water; both sulfur-based cofactors transfer organic groups to biomolecules. For TPP, various analytical tools point toward a simultaneous insertion of both heterocyclic rings into the electron-rich clip cavity. Similarly, SAM is also embedded with its sulfonium moiety inside the receptor cavity. This paves the way for enzyme models and direct interference with enzymatic processes. | lld:pubmed |
| pubmed-article:16323831 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16323831 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16323831 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16323831 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16323831 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16323831 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16323831 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16323831 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16323831 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:16323831 | pubmed:issn | 0022-3263 | lld:pubmed |
| pubmed-article:16323831 | pubmed:author | pubmed-author:PolkowskaJola... | lld:pubmed |
| pubmed-article:16323831 | pubmed:author | pubmed-author:SchraderThoma... | lld:pubmed |
| pubmed-article:16323831 | pubmed:author | pubmed-author:KlärnerFrank-... | lld:pubmed |
| pubmed-article:16323831 | pubmed:author | pubmed-author:FokkensMichae... | lld:pubmed |
| pubmed-article:16323831 | pubmed:author | pubmed-author:BastkowskiFra... | lld:pubmed |
| pubmed-article:16323831 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16323831 | pubmed:day | 9 | lld:pubmed |
| pubmed-article:16323831 | pubmed:volume | 70 | lld:pubmed |
| pubmed-article:16323831 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16323831 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16323831 | pubmed:pagination | 10227-37 | lld:pubmed |
| pubmed-article:16323831 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:16323831 | pubmed:meshHeading | pubmed-meshheading:16323831... | lld:pubmed |
| pubmed-article:16323831 | pubmed:meshHeading | pubmed-meshheading:16323831... | lld:pubmed |
| pubmed-article:16323831 | pubmed:meshHeading | pubmed-meshheading:16323831... | lld:pubmed |
| pubmed-article:16323831 | pubmed:meshHeading | pubmed-meshheading:16323831... | lld:pubmed |
| pubmed-article:16323831 | pubmed:meshHeading | pubmed-meshheading:16323831... | lld:pubmed |
| pubmed-article:16323831 | pubmed:meshHeading | pubmed-meshheading:16323831... | lld:pubmed |
| pubmed-article:16323831 | pubmed:meshHeading | pubmed-meshheading:16323831... | lld:pubmed |
| pubmed-article:16323831 | pubmed:meshHeading | pubmed-meshheading:16323831... | lld:pubmed |
| pubmed-article:16323831 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:16323831 | pubmed:articleTitle | Inclusion of thiamine diphosphate and S-adenosylmethionine at their chemically active sites. | lld:pubmed |
| pubmed-article:16323831 | pubmed:affiliation | Department of Chemistry, University of Marburg, Hans-Meerwein-Strasse, 35032 Marburg, Germany. schradet@staff.uni-marburg.de | lld:pubmed |
| pubmed-article:16323831 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16323831 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
