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pubmed-article:16317063pubmed:abstractTextOverweight and obesity are overrepresented in adolescents with type 1 diabetes mellitus (T1DM). Exogenous insulin administration often poorly reproduces normal insulin patterns and may less effectively regulate leptin and ghrelin, two hormones involved in the control of appetite and adiposity.lld:pubmed
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pubmed-article:16317063pubmed:articleTitleAdministration of Lispro insulin with meals improves glycemic control, increases circulating leptin, and suppresses ghrelin, compared with regular/NPH insulin in female patients with type 1 diabetes.lld:pubmed
pubmed-article:16317063pubmed:affiliationMedical Center, Patient Support and Services Building Suite G-400, University of California-Davis, 4150 V Street, Sacramento, CA 95817, USA. scgriffen@ucdavis.edulld:pubmed
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