| pubmed-article:16292312 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16292312 | lifeskim:mentions | umls-concept:C0670896 | lld:lifeskim |
| pubmed-article:16292312 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
| pubmed-article:16292312 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
| pubmed-article:16292312 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
| pubmed-article:16292312 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
| pubmed-article:16292312 | lifeskim:mentions | umls-concept:C2587213 | lld:lifeskim |
| pubmed-article:16292312 | pubmed:issue | 7066 | lld:pubmed |
| pubmed-article:16292312 | pubmed:dateCreated | 2005-11-18 | lld:pubmed |
| pubmed-article:16292312 | pubmed:abstractText | Toll-like receptors (TLRs) detect microbial infection and have an essential role in the induction of immune responses. TLRs can directly induce innate host defence responses, but the mechanisms of TLR-mediated control of adaptive immunity are not fully understood. Although TLR-induced dendritic cell maturation is required for activation of T-helper (T(H)) cells, the role of TLRs in B-cell activation and antibody production in vivo is not yet known. Here we show that activation and differentiation of T(H) cells is not sufficient for the induction of T-dependent B-cell responses. We find that, in addition to CD4+ T-cell help, generation of T-dependent antigen-specific antibody responses requires activation of TLRs in B cells. | lld:pubmed |
| pubmed-article:16292312 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16292312 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16292312 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16292312 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16292312 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16292312 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16292312 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16292312 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16292312 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16292312 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16292312 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16292312 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16292312 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:16292312 | pubmed:issn | 1476-4687 | lld:pubmed |
| pubmed-article:16292312 | pubmed:author | pubmed-author:MedzhitovRusl... | lld:pubmed |
| pubmed-article:16292312 | pubmed:author | pubmed-author:PasareChandra... | lld:pubmed |
| pubmed-article:16292312 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:16292312 | pubmed:day | 17 | lld:pubmed |
| pubmed-article:16292312 | pubmed:volume | 438 | lld:pubmed |
| pubmed-article:16292312 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16292312 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16292312 | pubmed:pagination | 364-8 | lld:pubmed |
| pubmed-article:16292312 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:16292312 | pubmed:meshHeading | pubmed-meshheading:16292312... | lld:pubmed |
| pubmed-article:16292312 | pubmed:meshHeading | pubmed-meshheading:16292312... | lld:pubmed |
| pubmed-article:16292312 | pubmed:meshHeading | pubmed-meshheading:16292312... | lld:pubmed |
| pubmed-article:16292312 | pubmed:meshHeading | pubmed-meshheading:16292312... | lld:pubmed |
| pubmed-article:16292312 | pubmed:meshHeading | pubmed-meshheading:16292312... | lld:pubmed |
| pubmed-article:16292312 | pubmed:meshHeading | pubmed-meshheading:16292312... | lld:pubmed |
| pubmed-article:16292312 | pubmed:meshHeading | pubmed-meshheading:16292312... | lld:pubmed |
| pubmed-article:16292312 | pubmed:meshHeading | pubmed-meshheading:16292312... | lld:pubmed |
| pubmed-article:16292312 | pubmed:meshHeading | pubmed-meshheading:16292312... | lld:pubmed |
| pubmed-article:16292312 | pubmed:meshHeading | pubmed-meshheading:16292312... | lld:pubmed |
| pubmed-article:16292312 | pubmed:meshHeading | pubmed-meshheading:16292312... | lld:pubmed |
| pubmed-article:16292312 | pubmed:meshHeading | pubmed-meshheading:16292312... | lld:pubmed |
| pubmed-article:16292312 | pubmed:meshHeading | pubmed-meshheading:16292312... | lld:pubmed |
| pubmed-article:16292312 | pubmed:meshHeading | pubmed-meshheading:16292312... | lld:pubmed |
| pubmed-article:16292312 | pubmed:meshHeading | pubmed-meshheading:16292312... | lld:pubmed |
| pubmed-article:16292312 | pubmed:meshHeading | pubmed-meshheading:16292312... | lld:pubmed |
| pubmed-article:16292312 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:16292312 | pubmed:articleTitle | Control of B-cell responses by Toll-like receptors. | lld:pubmed |
| pubmed-article:16292312 | pubmed:affiliation | Howard Hughes Medical Institute and Section of Immunobiology, Yale University School of Medicine, 300 Cedar Street New Haven, Connecticut 06510, USA. | lld:pubmed |
| pubmed-article:16292312 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16292312 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:16292312 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
| entrez-gene:17874 | entrezgene:pubmed | pubmed-article:16292312 | lld:entrezgene |
| entrez-gene:21898 | entrezgene:pubmed | pubmed-article:16292312 | lld:entrezgene |
| entrez-gene:21939 | entrezgene:pubmed | pubmed-article:16292312 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16292312 | lld:pubmed |
