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pubmed-article:16290765pubmed:abstractTextOrmosil (organically modified silane) such as n-octyl triethoxy silane has been found to aggregate in the form of normal micelles as well as reverse micelles in which the triethoxy silane moeities are hydrolyzed to form a hydrated silica network while the n-octyl groups are held together through hydrophobic interaction. These nanoparticles are spherical in shape and are nearly monodispersed with an average diameter of below 100 nm. The nanoparticles originating from the micellar aggregate have an hydrophobic core with a layer of the hydrated silica network at the surface. The hydrophobic core can host hydrophobic molecules such as tetraphenyl porphyrin, which is leached out of the particles extremely slowly compared to that in Triton X-100 micelles. The nanoparticles originating from the reverse micelles have a hydrated silica network in the core surrounded by the hydrophobic n-octyl chains on the particle surface. The hydrophilic silica cores of these nanoparticles have been used to encapsulate horseradish peroxidase (HRP) and the enzyme shows its activity and follows Michaelis-Menten kinetics.lld:pubmed
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pubmed-article:16290765pubmed:dateRevised2010-11-18lld:pubmed
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pubmed-article:16290765pubmed:articleTitleInorganic-organic hybrid nanoparticles from n-octyl triethoxy silane.lld:pubmed
pubmed-article:16290765pubmed:affiliationDepartment of Chemistry, University of Delhi, Delhi, 110007, India.lld:pubmed
pubmed-article:16290765pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:16290765pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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