Insulin resistance in skeletal muscle is a hallmark of type 2 diabetes. Therefore, we sought to identify and validate genes involved in the development of insulin resistance in skeletal muscle.
Gene expression profiling in skeletal muscle of Zucker diabetic fatty rats: implications for a role of stearoyl-CoA desaturase 1 in insulin resistance.
Sanofi-Aventis Deutschland GmbH, Science and Medical Affairs, TD Metabolism, Industriepark Hoechst, 65926 Frankfurt am Main, Germany. MarcDietrich.Voss@sanofi-aventis.com