| pubmed-article:16280092 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16280092 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:16280092 | lifeskim:mentions | umls-concept:C0034362 | lld:lifeskim |
| pubmed-article:16280092 | lifeskim:mentions | umls-concept:C0229671 | lld:lifeskim |
| pubmed-article:16280092 | lifeskim:mentions | umls-concept:C0003320 | lld:lifeskim |
| pubmed-article:16280092 | lifeskim:mentions | umls-concept:C0004358 | lld:lifeskim |
| pubmed-article:16280092 | lifeskim:mentions | umls-concept:C1979963 | lld:lifeskim |
| pubmed-article:16280092 | lifeskim:mentions | umls-concept:C0162801 | lld:lifeskim |
| pubmed-article:16280092 | lifeskim:mentions | umls-concept:C2003903 | lld:lifeskim |
| pubmed-article:16280092 | lifeskim:mentions | umls-concept:C0079603 | lld:lifeskim |
| pubmed-article:16280092 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
| pubmed-article:16280092 | pubmed:dateCreated | 2005-12-2 | lld:pubmed |
| pubmed-article:16280092 | pubmed:abstractText | Recent reports have shown that some of the immunological aspects of Q fever, a rickettsiosis caused by Coxiella burnetii, could be related to self-antigen responses. The aim of this study was to determine the specificity of the autoantibody response of patients with acute and chronic Coxiella infections. Smooth muscle and cardiac muscle-specific autoantibodies were observed in significant percentages in acutely or chronically affected Q fever patients when compared to healthy volunteers. Moreover, the incidence of cardiac muscle-specific autoantibody was significantly higher among chronically ill patients compared to acutely ill patients. Moreover, a band of 50 kD of a HeLa extract was detected in most of the sera of individuals with chronic infections and previous sequence analysis suggests that this antigen presents a high degree of homology with the human actin elongation factor 1 alpha. Further research would be necessary to confirm if antibodies to human cytoskeletal proteins could be of clinical importance in chronically infected Q fever patients. | lld:pubmed |
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| pubmed-article:16280092 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16280092 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16280092 | pubmed:status | PubMed-not-MEDLINE | lld:pubmed |
| pubmed-article:16280092 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:16280092 | pubmed:issn | 1740-2557 | lld:pubmed |
| pubmed-article:16280092 | pubmed:author | pubmed-author:TellezAA | lld:pubmed |
| pubmed-article:16280092 | pubmed:author | pubmed-author:SequíJJ | lld:pubmed |
| pubmed-article:16280092 | pubmed:author | pubmed-author:CamachoM TMT | lld:pubmed |
| pubmed-article:16280092 | pubmed:author | pubmed-author:OutschoornII | lld:pubmed |
| pubmed-article:16280092 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:16280092 | pubmed:day | 10 | lld:pubmed |
| pubmed-article:16280092 | pubmed:volume | 2 | lld:pubmed |
| pubmed-article:16280092 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16280092 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16280092 | pubmed:pagination | 10 | lld:pubmed |
| pubmed-article:16280092 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:16280092 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:16280092 | pubmed:articleTitle | Autoantibody profiles in the sera of patients with Q fever: characterization of antigens by immunofluorescence, immunoblot and sequence analysis. | lld:pubmed |
| pubmed-article:16280092 | pubmed:affiliation | Departamento de Orientación Diagnóstica. Centro Nacional de Microbiologia. Instituto de Salud Carlos III. Ctra. Majadahonda -Pozuelo Km 12,5. 28080-Madrid. Spain. mtcamacho@eresmas.com | lld:pubmed |
| pubmed-article:16280092 | pubmed:publicationType | Journal Article | lld:pubmed |
