| pubmed-article:16278297 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16278297 | lifeskim:mentions | umls-concept:C0231170 | lld:lifeskim |
| pubmed-article:16278297 | lifeskim:mentions | umls-concept:C0006104 | lld:lifeskim |
| pubmed-article:16278297 | lifeskim:mentions | umls-concept:C0521390 | lld:lifeskim |
| pubmed-article:16278297 | lifeskim:mentions | umls-concept:C0332281 | lld:lifeskim |
| pubmed-article:16278297 | lifeskim:mentions | umls-concept:C0034754 | lld:lifeskim |
| pubmed-article:16278297 | lifeskim:mentions | umls-concept:C1425339 | lld:lifeskim |
| pubmed-article:16278297 | lifeskim:mentions | umls-concept:C1527148 | lld:lifeskim |
| pubmed-article:16278297 | pubmed:issue | 47 | lld:pubmed |
| pubmed-article:16278297 | pubmed:dateCreated | 2005-11-23 | lld:pubmed |
| pubmed-article:16278297 | pubmed:abstractText | DYX2 on 6p22 is the most replicated reading disability (RD) locus. By saturating a previously identified peak of association with single nucleotide polymorphism markers, we identified a large polymorphic deletion that encodes tandem repeats of putative brain-related transcription factor binding sites in intron 2 of DCDC2. Alleles of this compound repeat are in significant disequilibrium with multiple reading traits. RT-PCR data show that DCDC2 localizes to the regions of the brain where fluent reading occurs, and RNA interference studies show that down-regulation alters neuronal migration. The statistical and functional studies are complementary and are consistent with the latest clinical imaging data for RD. Thus, we propose that DCDC2 is a candidate gene for RD. | lld:pubmed |
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| pubmed-article:16278297 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16278297 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16278297 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16278297 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16278297 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:16278297 | pubmed:issn | 0027-8424 | lld:pubmed |
| pubmed-article:16278297 | pubmed:author | pubmed-author:OlsonRichard... | lld:pubmed |
| pubmed-article:16278297 | pubmed:author | pubmed-author:PenningtonBru... | lld:pubmed |
| pubmed-article:16278297 | pubmed:author | pubmed-author:SmithShelley... | lld:pubmed |
| pubmed-article:16278297 | pubmed:author | pubmed-author:DeFriesJohn... | lld:pubmed |
| pubmed-article:16278297 | pubmed:author | pubmed-author:GelernterJoel... | lld:pubmed |
| pubmed-article:16278297 | pubmed:author | pubmed-author:WangYuY | lld:pubmed |
| pubmed-article:16278297 | pubmed:author | pubmed-author:SkudlarskiPaw... | lld:pubmed |
| pubmed-article:16278297 | pubmed:author | pubmed-author:SomloStefanS | lld:pubmed |
| pubmed-article:16278297 | pubmed:author | pubmed-author:ShaywitzSally... | lld:pubmed |
| pubmed-article:16278297 | pubmed:author | pubmed-author:ShaywitzBenne... | lld:pubmed |
| pubmed-article:16278297 | pubmed:author | pubmed-author:LoTurcoJoseph... | lld:pubmed |
| pubmed-article:16278297 | pubmed:author | pubmed-author:MengHaiyingH | lld:pubmed |
| pubmed-article:16278297 | pubmed:author | pubmed-author:GruenJeffrey... | lld:pubmed |
| pubmed-article:16278297 | pubmed:author | pubmed-author:PageGrier PGP | lld:pubmed |
| pubmed-article:16278297 | pubmed:author | pubmed-author:ParamasivamMu... | lld:pubmed |
| pubmed-article:16278297 | pubmed:author | pubmed-author:HagerKarlK | lld:pubmed |
| pubmed-article:16278297 | pubmed:author | pubmed-author:LiuJonathanJ | lld:pubmed |
| pubmed-article:16278297 | pubmed:author | pubmed-author:HeldMatthewM | lld:pubmed |
| pubmed-article:16278297 | pubmed:author | pubmed-author:O'Reilly-PolT... | lld:pubmed |
| pubmed-article:16278297 | pubmed:author | pubmed-author:MarchioneKare... | lld:pubmed |
| pubmed-article:16278297 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16278297 | pubmed:day | 22 | lld:pubmed |
| pubmed-article:16278297 | pubmed:volume | 102 | lld:pubmed |
| pubmed-article:16278297 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16278297 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16278297 | pubmed:pagination | 17053-8 | lld:pubmed |
| pubmed-article:16278297 | pubmed:dateRevised | 2011-5-5 | lld:pubmed |
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