pubmed-article:16276041 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:16276041 | lifeskim:mentions | umls-concept:C0071011 | lld:lifeskim |
pubmed-article:16276041 | lifeskim:mentions | umls-concept:C0007452 | lld:lifeskim |
pubmed-article:16276041 | lifeskim:mentions | umls-concept:C0010092 | lld:lifeskim |
pubmed-article:16276041 | lifeskim:mentions | umls-concept:C0312418 | lld:lifeskim |
pubmed-article:16276041 | lifeskim:mentions | umls-concept:C1521761 | lld:lifeskim |
pubmed-article:16276041 | lifeskim:mentions | umls-concept:C0870883 | lld:lifeskim |
pubmed-article:16276041 | lifeskim:mentions | umls-concept:C0036667 | lld:lifeskim |
pubmed-article:16276041 | pubmed:issue | 1 | lld:pubmed |
pubmed-article:16276041 | pubmed:dateCreated | 2006-3-15 | lld:pubmed |
pubmed-article:16276041 | pubmed:abstractText | The aim of this study was to examine whether active metabolites of phytoestrogens (equol and para-ethyl-phenol) inhibit sensitivity of bovine corpus luteum (CL) to luteinizing hormone (LH) and to auto/paracrine luteotropic factors (prostaglandin E2-PGE2 and prostaglandin F(2alpha)-PGF(2alpha)), and whether they influence pulsatile progesterone (P4) secretion by the bovine CL. In in vivo experiments, high levels of equol and para-ethyl-phenol were found in plasma and in the CL tissue of heifers and cows fed a soy bean diet (2.5 kg/animal/day), along with lower concentrations of P4 (P < 0.05). Both Prostaglandins (PG) and LH strongly stimulated P4 secretion in cultured pieces of CL that were collected from cows fed a standard diet (P < 0.01). There was no effect of PGs and LH on P4 stimulation in CLs obtained from cows fed a diet rich in soy bean. Finally, we examined whether active metabolites of phytoestrogens participated in regulation of pulsatile P4 secretion and LH-stimulated P4 secretion in vitro using a microdialysis system. Equol and para-ethyl-phenol had no effect on basic and pulsatile P4 secretion in CLs during 240 min of perfusion when compared to the control (P < 0.05). However, they inhibited LH-stimulated P4 secretion (P < 0.05). Phytoestrogens and their metabolites may disrupt CL function by inhibiting PG- and LH-stimulated P4 secretion. | lld:pubmed |
pubmed-article:16276041 | pubmed:language | eng | lld:pubmed |
pubmed-article:16276041 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16276041 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:16276041 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16276041 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16276041 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16276041 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16276041 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16276041 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16276041 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16276041 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16276041 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:16276041 | pubmed:month | Feb | lld:pubmed |
pubmed-article:16276041 | pubmed:issn | 0916-8818 | lld:pubmed |
pubmed-article:16276041 | pubmed:author | pubmed-author:SkarzynskiDar... | lld:pubmed |
pubmed-article:16276041 | pubmed:author | pubmed-author:BahMamadou... | lld:pubmed |
pubmed-article:16276041 | pubmed:author | pubmed-author:Woclawek-Poto... | lld:pubmed |
pubmed-article:16276041 | pubmed:author | pubmed-author:PilawskiWojci... | lld:pubmed |
pubmed-article:16276041 | pubmed:author | pubmed-author:PiskulaMarius... | lld:pubmed |
pubmed-article:16276041 | pubmed:author | pubmed-author:PiotrowskaKat... | lld:pubmed |
pubmed-article:16276041 | pubmed:author | pubmed-author:BoberAleksand... | lld:pubmed |
pubmed-article:16276041 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:16276041 | pubmed:volume | 52 | lld:pubmed |
pubmed-article:16276041 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:16276041 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:16276041 | pubmed:pagination | 33-41 | lld:pubmed |
pubmed-article:16276041 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
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pubmed-article:16276041 | pubmed:year | 2006 | lld:pubmed |
pubmed-article:16276041 | pubmed:articleTitle | Phytoestrogens and their metabolites inhibit the sensitivity of the bovine corpus luteum to luteotropic factors. | lld:pubmed |
pubmed-article:16276041 | pubmed:affiliation | Department of Reproductive Immunology, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn, Poland. | lld:pubmed |
pubmed-article:16276041 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:16276041 | pubmed:publicationType | In Vitro | lld:pubmed |
pubmed-article:16276041 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16276041 | lld:pubmed |