pubmed-article:1624466 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:1624466 | lifeskim:mentions | umls-concept:C0521009 | lld:lifeskim |
pubmed-article:1624466 | lifeskim:mentions | umls-concept:C0023810 | lld:lifeskim |
pubmed-article:1624466 | lifeskim:mentions | umls-concept:C1521991 | lld:lifeskim |
pubmed-article:1624466 | lifeskim:mentions | umls-concept:C0242808 | lld:lifeskim |
pubmed-article:1624466 | lifeskim:mentions | umls-concept:C0678594 | lld:lifeskim |
pubmed-article:1624466 | lifeskim:mentions | umls-concept:C0450363 | lld:lifeskim |
pubmed-article:1624466 | pubmed:issue | 14 | lld:pubmed |
pubmed-article:1624466 | pubmed:dateCreated | 1992-8-13 | lld:pubmed |
pubmed-article:1624466 | pubmed:abstractText | Molecular modelling techniques have been applied to calculate the three-dimensional architecture and the conformational flexibility of a complete bacterial S-form lipopolysaccharide (LPS) consisting of a hexaacyl lipid A identical to Escherichia coli lipid A, a complete Salmonella typhimurium core oligosaccharide portion, and four repeating units of the Salmonella serogroup B O-specific chain. X-ray powder diffraction experiments on dried samples of LPS were carried out to obtain information on the dimensions of the various LPS partial structures. Up to the Ra-LPS structure, the calculated model dimensions were in good agreement with experimental data and were 2.4 nm for lipid A, 2.8 nm for Re-LPS, 3.5 nm for Rd-LPS, and 4.4 nm for Ra-LPS. The maximum length of a stretched S-form LPS model bearing four repeating units was evaluated to be 9.6 nm; however, energetically favored LPS conformations showed the O-specific chain bent with respect to the Ra-LPS portion and significantly smaller dimensions (about 5.0 to 5.5 nm). According to the calculations, the Ra-LPS moiety has an approximately cylindrical shape and is conformationally well defined, in contrast to the O-specific chain, which was found to be the most flexible portion within the molecule. | lld:pubmed |
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pubmed-article:1624466 | pubmed:language | eng | lld:pubmed |
pubmed-article:1624466 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1624466 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:1624466 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1624466 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:1624466 | pubmed:month | Jul | lld:pubmed |
pubmed-article:1624466 | pubmed:issn | 0021-9193 | lld:pubmed |
pubmed-article:1624466 | pubmed:author | pubmed-author:BradaczekHH | lld:pubmed |
pubmed-article:1624466 | pubmed:author | pubmed-author:GutberletTT | lld:pubmed |
pubmed-article:1624466 | pubmed:author | pubmed-author:KastowskyMM | lld:pubmed |
pubmed-article:1624466 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:1624466 | pubmed:volume | 174 | lld:pubmed |
pubmed-article:1624466 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:1624466 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:1624466 | pubmed:pagination | 4798-806 | lld:pubmed |
pubmed-article:1624466 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
pubmed-article:1624466 | pubmed:meshHeading | pubmed-meshheading:1624466-... | lld:pubmed |
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pubmed-article:1624466 | pubmed:year | 1992 | lld:pubmed |
pubmed-article:1624466 | pubmed:articleTitle | Molecular modelling of the three-dimensional structure and conformational flexibility of bacterial lipopolysaccharide. | lld:pubmed |
pubmed-article:1624466 | pubmed:affiliation | Institut für Kristallographie, Freien Universität Berlin, Germany. | lld:pubmed |
pubmed-article:1624466 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:1624466 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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