pubmed-article:1622163 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:1622163 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
pubmed-article:1622163 | lifeskim:mentions | umls-concept:C0337611 | lld:lifeskim |
pubmed-article:1622163 | lifeskim:mentions | umls-concept:C0121772 | lld:lifeskim |
pubmed-article:1622163 | lifeskim:mentions | umls-concept:C0035608 | lld:lifeskim |
pubmed-article:1622163 | lifeskim:mentions | umls-concept:C0282515 | lld:lifeskim |
pubmed-article:1622163 | lifeskim:mentions | umls-concept:C2926735 | lld:lifeskim |
pubmed-article:1622163 | pubmed:issue | 3 | lld:pubmed |
pubmed-article:1622163 | pubmed:dateCreated | 1992-7-31 | lld:pubmed |
pubmed-article:1622163 | pubmed:abstractText | Rifampin is recommended as a prophylactic treatment for intimate contacts of young children who develop invasive infections with Haemophilus influenzae type B (Hib). A 4-day course of rifampin (20 mg/kg of body weight per day, not to exceed 600 mg as a maximum single daily dose) is 95% effective in eradicating pharyngeal colonization with Hib, thus effectively reducing the risk of both associated patients and recurrent illness in index patients less than 2 years old. This study compares rates of eradication of pharyngeal colonization with Hib for 2- and 4-day courses of rifampin therapy. One hundred sixty-three patients with Hib infection were treated at Children's Hospital of Pittsburgh between January 1986 and December 1988; prophylaxis was recommended for 128. Participating families were randomized to receive either 2- or 4-day therapy. Throat swabs were obtained from contacts prior to therapy. Repeat cultures were obtained from colonized contacts 2 days after completing rifampin and again on all contacts 7 to 10 days after completing therapy. Of 68 participating families, 34 received 2-day and 34 received 4-day therapy with rifampin. Twenty-two of 24 colonized contacts in the 2-day group and 17 of 18 in the 4-day group had negative cultures for Hib on follow-up. Two-day therapy with rifampin appears to be as effective as 4-day treatment in the eradication of Hib pharyngeal colonization. | lld:pubmed |
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pubmed-article:1622163 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1622163 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1622163 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1622163 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1622163 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1622163 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1622163 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1622163 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1622163 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1622163 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1622163 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1622163 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1622163 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1622163 | pubmed:language | eng | lld:pubmed |
pubmed-article:1622163 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1622163 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:1622163 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1622163 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:1622163 | pubmed:month | Mar | lld:pubmed |
pubmed-article:1622163 | pubmed:issn | 0066-4804 | lld:pubmed |
pubmed-article:1622163 | pubmed:author | pubmed-author:WaldE RER | lld:pubmed |
pubmed-article:1622163 | pubmed:author | pubmed-author:GreenMM | lld:pubmed |
pubmed-article:1622163 | pubmed:author | pubmed-author:GuerreJJ | lld:pubmed |
pubmed-article:1622163 | pubmed:author | pubmed-author:ByersCC | lld:pubmed |
pubmed-article:1622163 | pubmed:author | pubmed-author:LiK IKI | lld:pubmed |
pubmed-article:1622163 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:1622163 | pubmed:volume | 36 | lld:pubmed |
pubmed-article:1622163 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:1622163 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:1622163 | pubmed:pagination | 545-7 | lld:pubmed |
pubmed-article:1622163 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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pubmed-article:1622163 | pubmed:year | 1992 | lld:pubmed |
pubmed-article:1622163 | pubmed:articleTitle | Duration of rifampin chemoprophylaxis for contacts of patients infected with Haemophilus influenzae type B. | lld:pubmed |
pubmed-article:1622163 | pubmed:affiliation | Department of Pediatrics, University of Pittsburgh School of Medicine, Pennsylvania. | lld:pubmed |
pubmed-article:1622163 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:1622163 | pubmed:publicationType | Clinical Trial | lld:pubmed |
pubmed-article:1622163 | pubmed:publicationType | Comparative Study | lld:pubmed |
pubmed-article:1622163 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |