| pubmed-article:16220288 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16220288 | lifeskim:mentions | umls-concept:C0553662 | lld:lifeskim |
| pubmed-article:16220288 | lifeskim:mentions | umls-concept:C0008059 | lld:lifeskim |
| pubmed-article:16220288 | lifeskim:mentions | umls-concept:C0033325 | lld:lifeskim |
| pubmed-article:16220288 | lifeskim:mentions | umls-concept:C1706513 | lld:lifeskim |
| pubmed-article:16220288 | lifeskim:mentions | umls-concept:C0004083 | lld:lifeskim |
| pubmed-article:16220288 | lifeskim:mentions | umls-concept:C1882417 | lld:lifeskim |
| pubmed-article:16220288 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:16220288 | pubmed:dateCreated | 2006-5-10 | lld:pubmed |
| pubmed-article:16220288 | pubmed:abstractText | The objectives of this study were to determine genotypic and allelic frequencies of macrophage migration inhibitory factor (MIF) gene -173 G/C polymorphism in patients with juvenile rheumatoid arthritis (JRA) and to evaluate the association of the MIF -173 C allele with the outcome of JRA. Genomic DNA was collected from 67 JRA patients and 153 healthy individuals. To evaluate the association of the MIF -173 polymorphism with the outcome, we analyzed the data concerning the treatment regimen, duration of glucocorticoid treatment, score on the childhood health assessment questionnaire (C-HAQ) and the number of joints with active arthritis. Nonsignificant differences were observed between the study and control groups in the distribution of genotype and allele frequencies of the MIF gene -173 G/C polymorphism. In JRA patients, carrying a MIF -173 C allele, the number of disease modifying antirheumatic drugs required for the treatment was more, the duration of glucocorticoid treatment was significantly longer, and at the last visits the C-HAQ scores and the number of joints with active arthritis were significantly higher. MIF gene -173 C allele frequency did not differ between the controls and JRA patients. MIF -173 C allele did not confer increased susceptibility to JRA in our study group. Carriage of the MIF -173 C allele was found to be a strong predictor of poor outcome in all types of JRA. | lld:pubmed |
| pubmed-article:16220288 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16220288 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16220288 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16220288 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16220288 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16220288 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16220288 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:16220288 | pubmed:issn | 0172-8172 | lld:pubmed |
| pubmed-article:16220288 | pubmed:author | pubmed-author:LeventErtürkE | lld:pubmed |
| pubmed-article:16220288 | pubmed:author | pubmed-author:OzyürekArif... | lld:pubmed |
| pubmed-article:16220288 | pubmed:author | pubmed-author:GürsesDolunay... | lld:pubmed |
| pubmed-article:16220288 | pubmed:author | pubmed-author:UlgerZülalZ | lld:pubmed |
| pubmed-article:16220288 | pubmed:author | pubmed-author:BerdeliAfigA | lld:pubmed |
| pubmed-article:16220288 | pubmed:author | pubmed-author:SalarKorayK | lld:pubmed |
| pubmed-article:16220288 | pubmed:author | pubmed-author:GürpinarAli... | lld:pubmed |
| pubmed-article:16220288 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16220288 | pubmed:volume | 26 | lld:pubmed |
| pubmed-article:16220288 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16220288 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16220288 | pubmed:pagination | 726-31 | lld:pubmed |
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| pubmed-article:16220288 | pubmed:meshHeading | pubmed-meshheading:16220288... | lld:pubmed |
| pubmed-article:16220288 | pubmed:meshHeading | pubmed-meshheading:16220288... | lld:pubmed |
| pubmed-article:16220288 | pubmed:meshHeading | pubmed-meshheading:16220288... | lld:pubmed |
| pubmed-article:16220288 | pubmed:meshHeading | pubmed-meshheading:16220288... | lld:pubmed |
| pubmed-article:16220288 | pubmed:meshHeading | pubmed-meshheading:16220288... | lld:pubmed |
| pubmed-article:16220288 | pubmed:meshHeading | pubmed-meshheading:16220288... | lld:pubmed |
| pubmed-article:16220288 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:16220288 | pubmed:articleTitle | Association of macrophage migration inhibitory factor gene -173 G/C polymorphism with prognosis in Turkish children with juvenile rheumatoid arthritis. | lld:pubmed |
| pubmed-article:16220288 | pubmed:affiliation | Department of Pediatrics, Laboratory of Molecular Medicine, Ege University School of Medicine, Bornova, 35100, SSK Tepecik Hospital, Izmir, Turkey. afig@med.ege.edu.tr | lld:pubmed |
| pubmed-article:16220288 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16220288 | pubmed:publicationType | Comparative Study | lld:pubmed |
| entrez-gene:4282 | entrezgene:pubmed | pubmed-article:16220288 | lld:entrezgene |
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| lhgdn:association:14238 | lhgdn:found_in | pubmed-article:16220288 | lld:lhgdn |
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