| pubmed-article:1621817 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1621817 | lifeskim:mentions | umls-concept:C0034705 | lld:lifeskim |
| pubmed-article:1621817 | lifeskim:mentions | umls-concept:C0010124 | lld:lifeskim |
| pubmed-article:1621817 | lifeskim:mentions | umls-concept:C0005823 | lld:lifeskim |
| pubmed-article:1621817 | pubmed:issue | 6 Pt 2 | lld:pubmed |
| pubmed-article:1621817 | pubmed:dateCreated | 1992-8-4 | lld:pubmed |
| pubmed-article:1621817 | pubmed:abstractText | Evidence for increased glucocorticoid 6 beta-hydroxylation (enhanced family 3A cytochrome P-450 activity) is found in certain reversible forms of human hypertension. This association was investigated in the spontaneously hypertensive rat (SHR). The proportion of injected [3H]corticosterone excreted in urine as 6 beta-[3H]OH-corticosterone was four- to fivefold higher in SHR than in control Wistar-Kyoto rats, before and after development of overt hypertension. Both hypertension and 6 beta-hydroxylation were inhibited by troleandomycin (a selective inhibitor of family 3A cytochromes P-450), consistent with a role for increased steroid 6 beta-hydroxylation in the genesis of hypertension in the SHR. | lld:pubmed |
| pubmed-article:1621817 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1621817 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1621817 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1621817 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1621817 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1621817 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1621817 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1621817 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1621817 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1621817 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1621817 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:1621817 | pubmed:issn | 0002-9513 | lld:pubmed |
| pubmed-article:1621817 | pubmed:author | pubmed-author:SchoolwerthA... | lld:pubmed |
| pubmed-article:1621817 | pubmed:author | pubmed-author:WatlingtonC... | lld:pubmed |
| pubmed-article:1621817 | pubmed:author | pubmed-author:GroganW MWM | lld:pubmed |
| pubmed-article:1621817 | pubmed:author | pubmed-author:SchuetzE GEG | lld:pubmed |
| pubmed-article:1621817 | pubmed:author | pubmed-author:GuzelianPP | lld:pubmed |
| pubmed-article:1621817 | pubmed:author | pubmed-author:KramerL BLB | lld:pubmed |
| pubmed-article:1621817 | pubmed:author | pubmed-author:ZilaiJJ | lld:pubmed |
| pubmed-article:1621817 | pubmed:author | pubmed-author:GizekFF | lld:pubmed |
| pubmed-article:1621817 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1621817 | pubmed:volume | 262 | lld:pubmed |
| pubmed-article:1621817 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1621817 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1621817 | pubmed:pagination | F927-31 | lld:pubmed |
| pubmed-article:1621817 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:1621817 | pubmed:meshHeading | pubmed-meshheading:1621817-... | lld:pubmed |
| pubmed-article:1621817 | pubmed:meshHeading | pubmed-meshheading:1621817-... | lld:pubmed |
| pubmed-article:1621817 | pubmed:meshHeading | pubmed-meshheading:1621817-... | lld:pubmed |
| pubmed-article:1621817 | pubmed:meshHeading | pubmed-meshheading:1621817-... | lld:pubmed |
| pubmed-article:1621817 | pubmed:meshHeading | pubmed-meshheading:1621817-... | lld:pubmed |
| pubmed-article:1621817 | pubmed:meshHeading | pubmed-meshheading:1621817-... | lld:pubmed |
| pubmed-article:1621817 | pubmed:meshHeading | pubmed-meshheading:1621817-... | lld:pubmed |
| pubmed-article:1621817 | pubmed:meshHeading | pubmed-meshheading:1621817-... | lld:pubmed |
| pubmed-article:1621817 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1621817 | pubmed:articleTitle | Corticosterone 6 beta-hydroxylation correlates with blood pressure in spontaneously hypertensive rats. | lld:pubmed |
| pubmed-article:1621817 | pubmed:affiliation | Division of Endocrinology and Metabolism, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298-0145. | lld:pubmed |
| pubmed-article:1621817 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1621817 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:1621817 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1621817 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1621817 | lld:pubmed |
