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pubmed-article:16208702pubmed:abstractTextIt was previously demonstrated that PTEN protein expression is reduced in 67 of 236 (28%) breast carcinomas. Recent experimental studies suggested that the cell cycle inhibitor p27Kip1 (p27) is a downstream mediator through which PTEN negatively regulates cell cycle progression.lld:pubmed
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pubmed-article:16208702pubmed:copyrightInfoCopyright 2005 American Cancer Societylld:pubmed
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pubmed-article:16208702pubmed:articleTitleInactivation of PTEN is associated with a low p27Kip1 protein expression in breast carcinoma.lld:pubmed
pubmed-article:16208702pubmed:affiliationDepartment of Breast Surgery, Matsuyama Red Cross Hospital, Bunkyo, Matsuyama, Japan. tsutsui@lime.ocn.ne.jplld:pubmed
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