| pubmed-article:16201896 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16201896 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:16201896 | lifeskim:mentions | umls-concept:C0027051 | lld:lifeskim |
| pubmed-article:16201896 | lifeskim:mentions | umls-concept:C0553982 | lld:lifeskim |
| pubmed-article:16201896 | lifeskim:mentions | umls-concept:C0077401 | lld:lifeskim |
| pubmed-article:16201896 | lifeskim:mentions | umls-concept:C0242485 | lld:lifeskim |
| pubmed-article:16201896 | lifeskim:mentions | umls-concept:C0332196 | lld:lifeskim |
| pubmed-article:16201896 | lifeskim:mentions | umls-concept:C0336791 | lld:lifeskim |
| pubmed-article:16201896 | lifeskim:mentions | umls-concept:C0809949 | lld:lifeskim |
| pubmed-article:16201896 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:16201896 | pubmed:dateCreated | 2005-10-5 | lld:pubmed |
| pubmed-article:16201896 | pubmed:abstractText | Few studies have evaluated cardiac troponin I (cTnI) as a marker for infarct size and left ventricular (LV) dysfunction. Here we investigated the ability of a single-point cTnI, measured with a second-generation assay (Access AccuTnI), to estimate infarct size and assess LV function in patients with a first myocardial infarction (AMI). cTnI measurements were performed 12 and 48 h after admission in 63 consecutive AMI patients. LV function was evaluated by gated single-photon emission computed tomography (SPECT) and infarct size was estimated by CK-MB peak and SPECT myocardial perfusion. LV function and infarct size were evaluated by SPECT before hospital discharge. SPECT was also repeated 3 months later. Significant correlations (p<0.001) were found between cTnI at 12 and 48 h and both the peak CK-MB (r=0.61 and r=0.82, respectively) and the perfusion defect size at SPECT (r=0.55 and r=0.61, respectively). cTnI at 12 and 48 h were inversely related (p<0.001) to LV ejection fraction (LVEF) assessed both early (r=-0.45 and r=-0.57, respectively) and 3 months after AMI (r=-0.51 and r=-0.69, respectively). cTnI >14.8 microg/L at 48 h predicted an LVEF <40% at 3 months with a sensitivity of 100% [95% confidence interval (CI) 73.5-100%], specificity of 65% (CI 49-79%), and a negative predictive value of 100%. Our findings demonstrate that a single cTnI measurement 48 h after admission is useful for ruling out impaired LV function in a routine clinical setting. | lld:pubmed |
| pubmed-article:16201896 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16201896 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16201896 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16201896 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16201896 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16201896 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16201896 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16201896 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16201896 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16201896 | pubmed:issn | 1434-6621 | lld:pubmed |
| pubmed-article:16201896 | pubmed:author | pubmed-author:PanteghiniMau... | lld:pubmed |
| pubmed-article:16201896 | pubmed:author | pubmed-author:CucciaClaudio... | lld:pubmed |
| pubmed-article:16201896 | pubmed:author | pubmed-author:PaganiFrancaF | lld:pubmed |
| pubmed-article:16201896 | pubmed:author | pubmed-author:BonettiGrazie... | lld:pubmed |
| pubmed-article:16201896 | pubmed:author | pubmed-author:GiubbiniRaffa... | lld:pubmed |
| pubmed-article:16201896 | pubmed:author | pubmed-author:StefiniFrance... | lld:pubmed |
| pubmed-article:16201896 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16201896 | pubmed:volume | 43 | lld:pubmed |
| pubmed-article:16201896 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16201896 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16201896 | pubmed:pagination | 848-54 | lld:pubmed |
| pubmed-article:16201896 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:16201896 | pubmed:meshHeading | pubmed-meshheading:16201896... | lld:pubmed |
| pubmed-article:16201896 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:16201896 | pubmed:articleTitle | Measurement of troponin I 48 h after admission as a tool to rule out impaired left ventricular function in patients with a first myocardial infarction. | lld:pubmed |
| pubmed-article:16201896 | pubmed:affiliation | Dipartimento di Scienze Cliniche Luigi Sacco, Facoltà di Medicina e Chirurgia-Polo di Vialba, Università degli Studi di Milano, Milan, Italy. mauro.panteghini@unimi.it | lld:pubmed |
| pubmed-article:16201896 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16201896 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:16201896 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:16201896 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
