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pubmed-article:16198656pubmed:abstractTextAlthough cytochrome P450 (CYP) 2C9 was thought to be the main pathway for glyburide (INN, glibenclamide) metabolism in vivo, studies in vitro indicated that CYP2C19 had a more dominant effect. This study investigated the relative influence of CYP2C9 and CYP2C19 genotypes on the pharmacokinetics and pharmacodynamics of glyburide in Chinese subjects.lld:pubmed
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pubmed-article:16198656pubmed:articleTitleCYP2C9, but not CYP2C19, polymorphisms affect the pharmacokinetics and pharmacodynamics of glyburide in Chinese subjects.lld:pubmed
pubmed-article:16198656pubmed:affiliationSchool of Pharmacy and Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong. qpyin@cuhk.edu.hklld:pubmed
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