| pubmed-article:16198455 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16198455 | lifeskim:mentions | umls-concept:C0332307 | lld:lifeskim |
| pubmed-article:16198455 | lifeskim:mentions | umls-concept:C0074447 | lld:lifeskim |
| pubmed-article:16198455 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:16198455 | lifeskim:mentions | umls-concept:C0040549 | lld:lifeskim |
| pubmed-article:16198455 | lifeskim:mentions | umls-concept:C0040555 | lld:lifeskim |
| pubmed-article:16198455 | lifeskim:mentions | umls-concept:C0314603 | lld:lifeskim |
| pubmed-article:16198455 | lifeskim:mentions | umls-concept:C0805586 | lld:lifeskim |
| pubmed-article:16198455 | lifeskim:mentions | umls-concept:C1334043 | lld:lifeskim |
| pubmed-article:16198455 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:16198455 | pubmed:dateCreated | 2006-2-13 | lld:pubmed |
| pubmed-article:16198455 | pubmed:abstractText | Shiga toxin type 1 (Stx1) and type 2 (Stx2) are produced by Escherichia coli O157:H7 and are responsible for the life-threatening sequela, the hemolytic uremic syndrome. Whether antisera to Stx1 or Stx2 are cross-neutralizing remains controversial, so we constructed genetic toxoids of Stx1 and Stx2 and evaluated them as vaccines. Antisera from mice immunized with a single toxoid type recognized and neutralized the homologous toxin but not the heterologous toxin. Furthermore, only mice immunized with Stx1 and Stx2 toxoids were protected against a lethal challenge of both toxins. We conclude that Stx1 and Stx2 are distinct antigens for mice. | lld:pubmed |
| pubmed-article:16198455 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16198455 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16198455 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16198455 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16198455 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16198455 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16198455 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16198455 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16198455 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16198455 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:16198455 | pubmed:issn | 0264-410X | lld:pubmed |
| pubmed-article:16198455 | pubmed:author | pubmed-author:O'BrienAlison... | lld:pubmed |
| pubmed-article:16198455 | pubmed:author | pubmed-author:TeelLouise... | lld:pubmed |
| pubmed-article:16198455 | pubmed:author | pubmed-author:JudgeNicole... | lld:pubmed |
| pubmed-article:16198455 | pubmed:author | pubmed-author:WenSharon XSX | lld:pubmed |
| pubmed-article:16198455 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16198455 | pubmed:day | 20 | lld:pubmed |
| pubmed-article:16198455 | pubmed:volume | 24 | lld:pubmed |
| pubmed-article:16198455 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16198455 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16198455 | pubmed:pagination | 1142-8 | lld:pubmed |
| pubmed-article:16198455 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
| pubmed-article:16198455 | pubmed:meshHeading | pubmed-meshheading:16198455... | lld:pubmed |
| pubmed-article:16198455 | pubmed:meshHeading | pubmed-meshheading:16198455... | lld:pubmed |
| pubmed-article:16198455 | pubmed:meshHeading | pubmed-meshheading:16198455... | lld:pubmed |
| pubmed-article:16198455 | pubmed:meshHeading | pubmed-meshheading:16198455... | lld:pubmed |
| pubmed-article:16198455 | pubmed:meshHeading | pubmed-meshheading:16198455... | lld:pubmed |
| pubmed-article:16198455 | pubmed:meshHeading | pubmed-meshheading:16198455... | lld:pubmed |
| pubmed-article:16198455 | pubmed:meshHeading | pubmed-meshheading:16198455... | lld:pubmed |
| pubmed-article:16198455 | pubmed:meshHeading | pubmed-meshheading:16198455... | lld:pubmed |
| pubmed-article:16198455 | pubmed:meshHeading | pubmed-meshheading:16198455... | lld:pubmed |
| pubmed-article:16198455 | pubmed:meshHeading | pubmed-meshheading:16198455... | lld:pubmed |
| pubmed-article:16198455 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:16198455 | pubmed:articleTitle | Genetic toxoids of Shiga toxin types 1 and 2 protect mice against homologous but not heterologous toxin challenge. | lld:pubmed |
| pubmed-article:16198455 | pubmed:affiliation | Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, B4052, 4301 Jones Bridge Road, Bethesda, MD 20814-4799, USA. | lld:pubmed |
| pubmed-article:16198455 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16198455 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:16198455 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16198455 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16198455 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16198455 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16198455 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16198455 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16198455 | lld:pubmed |
