pubmed-article:1616954 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:1616954 | lifeskim:mentions | umls-concept:C0028953 | lld:lifeskim |
pubmed-article:1616954 | lifeskim:mentions | umls-concept:C0184511 | lld:lifeskim |
pubmed-article:1616954 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
pubmed-article:1616954 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
pubmed-article:1616954 | lifeskim:mentions | umls-concept:C1317973 | lld:lifeskim |
pubmed-article:1616954 | lifeskim:mentions | umls-concept:C0183683 | lld:lifeskim |
pubmed-article:1616954 | lifeskim:mentions | umls-concept:C0344211 | lld:lifeskim |
pubmed-article:1616954 | lifeskim:mentions | umls-concept:C1521721 | lld:lifeskim |
pubmed-article:1616954 | lifeskim:mentions | umls-concept:C1171411 | lld:lifeskim |
pubmed-article:1616954 | pubmed:issue | 1 | lld:pubmed |
pubmed-article:1616954 | pubmed:dateCreated | 1992-8-5 | lld:pubmed |
pubmed-article:1616954 | pubmed:abstractText | A new controlled-pore glass (CPG) support is described that allows for the direct synthesis of oligonucleotides bearing a 3'-aminohexyl tail. This solid support (AH-CPG) exhibits superior performance as compared to a commercially available 3'-amine CPG. The AH-CPG is prepared from 6-aminohexan-1-ol with a unique protecting group for the amine that also functions as the site of attachment to the CPG. A 3'-amine-tailed oligodeoxynucleotide (ODN) was prepared from this support using standard phosphoramidite coupling and deprotection conditions. The 3'-amine-tailed ODN was subsequently modified with an acridinylpropionic acid tetrafluorophenyl ester. Facile synthesis of the AH-CPG and the stability of the deprotected product makes this functionalized solid support especially useful for preparation of oligonucleotides bearing 3'-amine tails and other modifications. | lld:pubmed |
pubmed-article:1616954 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1616954 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1616954 | pubmed:language | eng | lld:pubmed |
pubmed-article:1616954 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1616954 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:1616954 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1616954 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1616954 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:1616954 | pubmed:issn | 1043-1802 | lld:pubmed |
pubmed-article:1616954 | pubmed:author | pubmed-author:MeyerR BRBJr | lld:pubmed |
pubmed-article:1616954 | pubmed:author | pubmed-author:ReedM WMW | lld:pubmed |
pubmed-article:1616954 | pubmed:author | pubmed-author:AdamsA DAD | lld:pubmed |
pubmed-article:1616954 | pubmed:author | pubmed-author:PetrieC RCR | lld:pubmed |
pubmed-article:1616954 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:1616954 | pubmed:volume | 3 | lld:pubmed |
pubmed-article:1616954 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:1616954 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:1616954 | pubmed:pagination | 85-7 | lld:pubmed |
pubmed-article:1616954 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
pubmed-article:1616954 | pubmed:meshHeading | pubmed-meshheading:1616954-... | lld:pubmed |
pubmed-article:1616954 | pubmed:meshHeading | pubmed-meshheading:1616954-... | lld:pubmed |
pubmed-article:1616954 | pubmed:meshHeading | pubmed-meshheading:1616954-... | lld:pubmed |
pubmed-article:1616954 | pubmed:meshHeading | pubmed-meshheading:1616954-... | lld:pubmed |
pubmed-article:1616954 | pubmed:articleTitle | An improved CPG support for the synthesis of 3'-amine-tailed oligonucleotides. | lld:pubmed |
pubmed-article:1616954 | pubmed:affiliation | MicroProbe Corporation, Bothell, Washington 98021. | lld:pubmed |
pubmed-article:1616954 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:1616954 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
pubmed-article:1616954 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1616954 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1616954 | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1616954 | lld:pubmed |