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pubmed-article:16165703pubmed:abstractTextNicotinamide has been shown to inhibit proliferation and induce apoptosis in a variety of cells. Moreover, nicotinamide treatment attenuates collagen accumulation and fibrogenesis in the bleomycin model of lung fibrosis. We hypothesized that nicotinamide may be useful as an antifibrotic agent in liver fibrosis and we investigated the in vitro effect of nicotinamide on hepatic stellate cells proliferation, apoptosis and collagen I expression.lld:pubmed
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pubmed-article:16165703pubmed:articleTitleNicotinamide induces apoptosis and reduces collagen I and pro-inflammatory cytokines expression in rat hepatic stellate cells.lld:pubmed
pubmed-article:16165703pubmed:affiliationLiver Unit, Gastroenterology Institute, and Tel Aviv, Israel.lld:pubmed
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