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pubmed-article:16153938pubmed:abstractTextTransplantation is limited by a lack of human organ donors. Organs derived from animals, most likely the pig, represent a potential solution to this problem. For the heart, 90-day median graft survival of life-supporting pig hearts transplanted to nonhuman primates has been considered a reasonable standard for entry into the clinical arena. Overcoming the immune barrier to successful cardiac xenotransplantation is most appropriately first explored with the non-life-supporting heterotopic model.lld:pubmed
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pubmed-article:16153938pubmed:articleTitleCardiac xenotransplantation: recent preclinical progress with 3-month median survival.lld:pubmed
pubmed-article:16153938pubmed:affiliationDivision of Cardiovascular Surgery, Department of Surgery, Mayo Clinic, Rochester, Minn 55905, USA. mcgregor.christopher@mayo.edulld:pubmed
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