| pubmed-article:16150588 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16150588 | lifeskim:mentions | umls-concept:C0015450 | lld:lifeskim |
| pubmed-article:16150588 | lifeskim:mentions | umls-concept:C0521390 | lld:lifeskim |
| pubmed-article:16150588 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
| pubmed-article:16150588 | lifeskim:mentions | umls-concept:C1655731 | lld:lifeskim |
| pubmed-article:16150588 | lifeskim:mentions | umls-concept:C0035253 | lld:lifeskim |
| pubmed-article:16150588 | lifeskim:mentions | umls-concept:C1419346 | lld:lifeskim |
| pubmed-article:16150588 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:16150588 | pubmed:dateCreated | 2005-10-5 | lld:pubmed |
| pubmed-article:16150588 | pubmed:abstractText | Nervous system development relies on a complex signaling network to engineer the orderly transitions that lead to the acquisition of a neural cell fate. Progression from the non-neuronal pluripotent stem cell to a restricted neural lineage is characterized by distinct patterns of gene expression, particularly the restriction of neuronal gene expression to neurons. Concurrently, cells outside the nervous system acquire and maintain a non-neuronal fate that permanently excludes expression of neuronal genes. Studies of the transcriptional repressor REST, which regulates a large network of neuronal genes, provide a paradigm for elucidating the link between epigenetic mechanisms and neurogenesis. REST orchestrates a set of epigenetic modifications that are distinct between non-neuronal cells that give rise to neurons and those that are destined to remain as nervous system outsiders. | lld:pubmed |
| pubmed-article:16150588 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16150588 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16150588 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16150588 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:16150588 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16150588 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16150588 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:16150588 | pubmed:issn | 0959-4388 | lld:pubmed |
| pubmed-article:16150588 | pubmed:author | pubmed-author:MandelGailG | lld:pubmed |
| pubmed-article:16150588 | pubmed:author | pubmed-author:BallasNuritN | lld:pubmed |
| pubmed-article:16150588 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16150588 | pubmed:volume | 15 | lld:pubmed |
| pubmed-article:16150588 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16150588 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16150588 | pubmed:pagination | 500-6 | lld:pubmed |
| pubmed-article:16150588 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:16150588 | pubmed:meshHeading | pubmed-meshheading:16150588... | lld:pubmed |
| pubmed-article:16150588 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:16150588 | pubmed:articleTitle | The many faces of REST oversee epigenetic programming of neuronal genes. | lld:pubmed |
| pubmed-article:16150588 | pubmed:affiliation | Howard Hughes Medical Institute, Department of Neurobiology and Behavior, State University of New York, Stony Brook, NY 11794, USA. | lld:pubmed |
| pubmed-article:16150588 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16150588 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:16150588 | pubmed:publicationType | Review | lld:pubmed |
| pubmed-article:16150588 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:16150588 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
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