pubmed-article:16146539 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:16146539 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
pubmed-article:16146539 | lifeskim:mentions | umls-concept:C0008059 | lld:lifeskim |
pubmed-article:16146539 | lifeskim:mentions | umls-concept:C0684224 | lld:lifeskim |
pubmed-article:16146539 | lifeskim:mentions | umls-concept:C0010980 | lld:lifeskim |
pubmed-article:16146539 | lifeskim:mentions | umls-concept:C0272293 | lld:lifeskim |
pubmed-article:16146539 | pubmed:issue | 4 | lld:pubmed |
pubmed-article:16146539 | pubmed:dateCreated | 2005-9-8 | lld:pubmed |
pubmed-article:16146539 | pubmed:abstractText | Data on 90 patients (55 adults and 35 children) with chronic idiopathic thrombocytopenic purpura (ITP) and a platelet count of <50 x 10(9)/L treated with dapsone at a dose of 1-2 mg/kg/d are presented. A response was observed in 57 (63.3%) patients. The average time for response was 3.5 months (range 1-9) and the average duration of treatment with dapsone was 10.4 months (range 4-14). Overall response rates of 65.7% and 61.8% were observed in children and adults respectively. Side effects requiring discontinuation of therapy were observed in three (2%) patients. These results demonstrate that dapsone is an effective, inexpensive and well-tolerated treatment for chronic ITP, in both children and adults and could be considered for patients who fail steroid therapy. | lld:pubmed |
pubmed-article:16146539 | pubmed:language | eng | lld:pubmed |
pubmed-article:16146539 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16146539 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:16146539 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:16146539 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:16146539 | pubmed:month | Oct | lld:pubmed |
pubmed-article:16146539 | pubmed:issn | 0902-4441 | lld:pubmed |
pubmed-article:16146539 | pubmed:author | pubmed-author:GeorgeBijuB | lld:pubmed |
pubmed-article:16146539 | pubmed:author | pubmed-author:SrivastavaAlo... | lld:pubmed |
pubmed-article:16146539 | pubmed:author | pubmed-author:MathewsVikram... | lld:pubmed |
pubmed-article:16146539 | pubmed:author | pubmed-author:ChandyMammenM | lld:pubmed |
pubmed-article:16146539 | pubmed:author | pubmed-author:DamodarSharat... | lld:pubmed |
pubmed-article:16146539 | pubmed:author | pubmed-author:ViswabandyaAu... | lld:pubmed |
pubmed-article:16146539 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:16146539 | pubmed:volume | 75 | lld:pubmed |
pubmed-article:16146539 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:16146539 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:16146539 | pubmed:pagination | 328-31 | lld:pubmed |
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pubmed-article:16146539 | pubmed:year | 2005 | lld:pubmed |
pubmed-article:16146539 | pubmed:articleTitle | Dapsone for chronic idiopathic thrombocytopenic purpura in children and adults--a report on 90 patients. | lld:pubmed |
pubmed-article:16146539 | pubmed:affiliation | Department of Haematology, Christian Medical College, Vellore-632004, Tamil Nadu, India. | lld:pubmed |
pubmed-article:16146539 | pubmed:publicationType | Journal Article | lld:pubmed |