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pubmed-article:16146205pubmed:abstractTextLung involvement is rare in Waldenström macroglobulinemia (WM). We encountered a male patient with WM who complained of breathlessness. Chest X-ray revealed diffuse infiltrative shadow throughout the both lungs. Transbronchial biopsy showed infiltration of atypical plasmacytoid lymphocytes and non-caseating granuloma. We treated the patients with fludarabine phosphate, and both his symptom and X-ray findings were then improved. To our knowledge, this is the first case showing non-caseating granuloma with lung involvement of WM. We discuss a mechanism of non-caseating granuloma formation in this case.lld:pubmed
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pubmed-article:16146205pubmed:dateRevised2008-11-21lld:pubmed
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pubmed-article:16146205pubmed:articleTitlePulmonary non-caseating granuloma in Waldenström macroglobulinemia.lld:pubmed
pubmed-article:16146205pubmed:affiliationDepartment of Internal Medicine, Tokai University School of Medicine, Kanagawa, Japan. f.ryuki@is.icc.u-tokai.ac.jplld:pubmed
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