Linked Life Data

16144372

Source:http://linkedlifedata.com/resource/pubmed/id/16144372

Statements in which the resource exists.
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pubmed-article:16144372pubmed:abstractTextSynthetic hemigramicidin S-peptidyl TEMPO conjugates are effectively delivered into cells and mitochondria, where they act as electron scavengers and exert protection against apoptosis. Our delivery approach is based on the use of specific structural signaling features recognizable by cells as mitochondria targeting sequences and offers considerable therapeutic anti-apoptotic potential.lld:pubmed
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pubmed-article:16144372pubmed:articleTitleMitochondrial targeting of selective electron scavengers: synthesis and biological analysis of hemigramicidin-TEMPO conjugates.lld:pubmed
pubmed-article:16144372pubmed:affiliationDepartment of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA. pwipf@pitt.edulld:pubmed
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