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pubmed-article:16140027pubmed:abstractTextAsthma is characterized by increased recruitment of inflammatory cells from the circulation into the airways. As selectins mediate tethering and rolling of leukocytes on the vascular endothelium, they constitute a promising target for the therapeutic modulation of inflammation. We evaluated the effect of inhaled bimosiamose (TBC1269), a synthetic pan-selectin antagonist, on allergen-induced late asthmatic reactions (LAR) in mild asthmatics.lld:pubmed
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pubmed-article:16140027pubmed:articleTitleBimosiamose, an inhaled small-molecule pan-selectin antagonist, attenuates late asthmatic reactions following allergen challenge in mild asthmatics: a randomized, double-blind, placebo-controlled clinical cross-over-trial.lld:pubmed
pubmed-article:16140027pubmed:affiliationPulmonary Department, Internal Medicine, University Hospital, Mainz, Germany. k.beeh@insaf-wi.delld:pubmed
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pubmed-article:16140027pubmed:publicationTypeRandomized Controlled Triallld:pubmed
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