| pubmed-article:16126250 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16126250 | lifeskim:mentions | umls-concept:C0024299 | lld:lifeskim |
| pubmed-article:16126250 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:16126250 | lifeskim:mentions | umls-concept:C0521451 | lld:lifeskim |
| pubmed-article:16126250 | lifeskim:mentions | umls-concept:C0015663 | lld:lifeskim |
| pubmed-article:16126250 | lifeskim:mentions | umls-concept:C0162772 | lld:lifeskim |
| pubmed-article:16126250 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:16126250 | lifeskim:mentions | umls-concept:C0033268 | lld:lifeskim |
| pubmed-article:16126250 | lifeskim:mentions | umls-concept:C0021149 | lld:lifeskim |
| pubmed-article:16126250 | pubmed:issue | 11 | lld:pubmed |
| pubmed-article:16126250 | pubmed:dateCreated | 2005-9-28 | lld:pubmed |
| pubmed-article:16126250 | pubmed:abstractText | There is currently of a great interest investigating the role of nutrition in the prevention of age-associated disorders. The present study aimed to evaluate, on a particular strain of mice, the efficacy of alternate-day fasting on the mitochondrial production of free radical species and on the incidence of a specific cancer (lymphoma) in aged mice. Alternate fasting, that was initiated in middle age mice through a 4 month period, reduced significantly the incidence of lymphoma (0% versus 33% for controls). No remarkable difference was observed in the overall food consumption between alternate-fed (AF) and ad libitum (AL) mice, suggesting that the efficacy of alternate fasting did not really depend on calorie restriction. A significant decrease in the mitochondrial generation of reactive oxygen species (ROS) that was associated with a significant increase in spleen mitochondria SOD activity was observed when mice were maintained on intermittent fasting. Our results suggest that alternate fasting could exert a beneficial antioxidant effect and a modulation of the oxidative stress associated with aging. | lld:pubmed |
| pubmed-article:16126250 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16126250 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16126250 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16126250 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16126250 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16126250 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16126250 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16126250 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16126250 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16126250 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:16126250 | pubmed:issn | 0047-6374 | lld:pubmed |
| pubmed-article:16126250 | pubmed:author | pubmed-author:RousselAnne-M... | lld:pubmed |
| pubmed-article:16126250 | pubmed:author | pubmed-author:RiondelJacque... | lld:pubmed |
| pubmed-article:16126250 | pubmed:author | pubmed-author:DucrosVéroniq... | lld:pubmed |
| pubmed-article:16126250 | pubmed:author | pubmed-author:DescampsOlivi... | lld:pubmed |
| pubmed-article:16126250 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16126250 | pubmed:volume | 126 | lld:pubmed |
| pubmed-article:16126250 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16126250 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16126250 | pubmed:pagination | 1185-91 | lld:pubmed |
| pubmed-article:16126250 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:16126250 | pubmed:meshHeading | pubmed-meshheading:16126250... | lld:pubmed |
| pubmed-article:16126250 | pubmed:meshHeading | pubmed-meshheading:16126250... | lld:pubmed |
| pubmed-article:16126250 | pubmed:meshHeading | pubmed-meshheading:16126250... | lld:pubmed |
| pubmed-article:16126250 | pubmed:meshHeading | pubmed-meshheading:16126250... | lld:pubmed |
| pubmed-article:16126250 | pubmed:meshHeading | pubmed-meshheading:16126250... | lld:pubmed |
| pubmed-article:16126250 | pubmed:meshHeading | pubmed-meshheading:16126250... | lld:pubmed |
| pubmed-article:16126250 | pubmed:meshHeading | pubmed-meshheading:16126250... | lld:pubmed |
| pubmed-article:16126250 | pubmed:meshHeading | pubmed-meshheading:16126250... | lld:pubmed |
| pubmed-article:16126250 | pubmed:meshHeading | pubmed-meshheading:16126250... | lld:pubmed |
| pubmed-article:16126250 | pubmed:meshHeading | pubmed-meshheading:16126250... | lld:pubmed |
| pubmed-article:16126250 | pubmed:meshHeading | pubmed-meshheading:16126250... | lld:pubmed |
| pubmed-article:16126250 | pubmed:meshHeading | pubmed-meshheading:16126250... | lld:pubmed |
| pubmed-article:16126250 | pubmed:meshHeading | pubmed-meshheading:16126250... | lld:pubmed |
| pubmed-article:16126250 | pubmed:meshHeading | pubmed-meshheading:16126250... | lld:pubmed |
| pubmed-article:16126250 | pubmed:meshHeading | pubmed-meshheading:16126250... | lld:pubmed |
| pubmed-article:16126250 | pubmed:meshHeading | pubmed-meshheading:16126250... | lld:pubmed |
| pubmed-article:16126250 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:16126250 | pubmed:articleTitle | Mitochondrial production of reactive oxygen species and incidence of age-associated lymphoma in OF1 mice: effect of alternate-day fasting. | lld:pubmed |
| pubmed-article:16126250 | pubmed:affiliation | Laboratoire de Nutrition, Vieillissement, Maladies Cardio-vasculaires, Faculté de Pharmacie, Université de Grenoble, Domaine de la Merci, 38706 la Tronche, France. | lld:pubmed |
| pubmed-article:16126250 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16126250 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:16948 | entrezgene:pubmed | pubmed-article:16126250 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16126250 | lld:pubmed |
