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pubmed-article:16122554pubmed:abstractTextCytokine activation of endothelial cell monolayers is associated with cell detachment, microparticle shedding from plasma membranes, and phosphatidylserine appearance in the plasma membrane outer leaflets. While tissue factor expression on activated endothelial cells and microparticles is well documented, the contribution of detached endothelial cells to tissue factor activity is less clear. We studied tissue factor expression and the role of tissue factor pathway inhibitor on adherent and detached endothelial cells and on microparticles following endothelial cell activation with TNF-alpha.lld:pubmed
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pubmed-article:16122554pubmed:year2005lld:pubmed
pubmed-article:16122554pubmed:articleTitleDetached endothelial cells and microparticles as sources of tissue factor activity.lld:pubmed
pubmed-article:16122554pubmed:affiliationPediatric Hematology/Oncology, MassGeneral Hospital for Children, Harvard Medical School, Boston, MA 02114, USA.lld:pubmed
pubmed-article:16122554pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:16122554pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
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