The combination of the farnesyl transferase inhibitor lonafarnib and the proteasome inhibitor bortezomib induces synergistic apoptosis in human myeloma cells that is associated with down-regulation of p-AKT.

Source:http://linkedlifedata.com/resource/pubmed/id/16118318

Blood 2005 Dec 15 106 13 4322-9

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PMID
16118318