| pubmed-article:16117816 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16117816 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:16117816 | lifeskim:mentions | umls-concept:C0036536 | lld:lifeskim |
| pubmed-article:16117816 | lifeskim:mentions | umls-concept:C0036537 | lld:lifeskim |
| pubmed-article:16117816 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:16117816 | lifeskim:mentions | umls-concept:C0205359 | lld:lifeskim |
| pubmed-article:16117816 | lifeskim:mentions | umls-concept:C0695347 | lld:lifeskim |
| pubmed-article:16117816 | lifeskim:mentions | umls-concept:C0302350 | lld:lifeskim |
| pubmed-article:16117816 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:16117816 | pubmed:dateCreated | 2005-8-24 | lld:pubmed |
| pubmed-article:16117816 | pubmed:abstractText | Three major therapeutic modalities (transsphenoidal surgery, radiotherapy and medical therapy) are currently available for acromegaly. Although surgery is regarded as the primary option, 50--60% of macroadenomas require further treatment in the form of radiotherapy and/or medical therapy. Recent studies have suggested that radiotherapy might damage the normal hypothalamic-pituitary axis and also rarely leads to IGF-I normalization. The aims of this study were: (1) to examine the effect of different therapeutic modalities (transsphenoidal surgery, TSS; radiotherapy, RT; medical treatment with somatostatin analogues, SSA) on the daily spontaneous GH secretory pattern (day curve); and (2) to determine the relationship between the characteristics of the GH secretory pattern and the circulating concentration of IGF-I, acid-labile subunit (ALS) and IGFBP-3. | lld:pubmed |
| pubmed-article:16117816 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16117816 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16117816 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16117816 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16117816 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16117816 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16117816 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16117816 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16117816 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16117816 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16117816 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16117816 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16117816 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:16117816 | pubmed:issn | 0300-0664 | lld:pubmed |
| pubmed-article:16117816 | pubmed:author | pubmed-author:BarrecaAntoni... | lld:pubmed |
| pubmed-article:16117816 | pubmed:author | pubmed-author:GiustiMassimo... | lld:pubmed |
| pubmed-article:16117816 | pubmed:author | pubmed-author:FeroneDiegoD | lld:pubmed |
| pubmed-article:16117816 | pubmed:author | pubmed-author:MinutoFrances... | lld:pubmed |
| pubmed-article:16117816 | pubmed:author | pubmed-author:SidotiMarilen... | lld:pubmed |
| pubmed-article:16117816 | pubmed:author | pubmed-author:ResminiEugeni... | lld:pubmed |
| pubmed-article:16117816 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16117816 | pubmed:volume | 63 | lld:pubmed |
| pubmed-article:16117816 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16117816 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16117816 | pubmed:pagination | 294-7 | lld:pubmed |
| pubmed-article:16117816 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:16117816 | pubmed:meshHeading | pubmed-meshheading:16117816... | lld:pubmed |
| pubmed-article:16117816 | pubmed:meshHeading | pubmed-meshheading:16117816... | lld:pubmed |
| pubmed-article:16117816 | pubmed:meshHeading | pubmed-meshheading:16117816... | lld:pubmed |
| pubmed-article:16117816 | pubmed:meshHeading | pubmed-meshheading:16117816... | lld:pubmed |
| pubmed-article:16117816 | pubmed:meshHeading | pubmed-meshheading:16117816... | lld:pubmed |
| pubmed-article:16117816 | pubmed:meshHeading | pubmed-meshheading:16117816... | lld:pubmed |
| pubmed-article:16117816 | pubmed:meshHeading | pubmed-meshheading:16117816... | lld:pubmed |
| pubmed-article:16117816 | pubmed:meshHeading | pubmed-meshheading:16117816... | lld:pubmed |
| pubmed-article:16117816 | pubmed:meshHeading | pubmed-meshheading:16117816... | lld:pubmed |
| pubmed-article:16117816 | pubmed:meshHeading | pubmed-meshheading:16117816... | lld:pubmed |
| pubmed-article:16117816 | pubmed:meshHeading | pubmed-meshheading:16117816... | lld:pubmed |
| pubmed-article:16117816 | pubmed:meshHeading | pubmed-meshheading:16117816... | lld:pubmed |
| pubmed-article:16117816 | pubmed:meshHeading | pubmed-meshheading:16117816... | lld:pubmed |
| pubmed-article:16117816 | pubmed:meshHeading | pubmed-meshheading:16117816... | lld:pubmed |
| pubmed-article:16117816 | pubmed:meshHeading | pubmed-meshheading:16117816... | lld:pubmed |
| pubmed-article:16117816 | pubmed:meshHeading | pubmed-meshheading:16117816... | lld:pubmed |
| pubmed-article:16117816 | pubmed:meshHeading | pubmed-meshheading:16117816... | lld:pubmed |
| pubmed-article:16117816 | pubmed:meshHeading | pubmed-meshheading:16117816... | lld:pubmed |
| pubmed-article:16117816 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:16117816 | pubmed:articleTitle | Effect of different therapeutic modalities on spontaneous GH secretion in acromegalic patients. | lld:pubmed |
| pubmed-article:16117816 | pubmed:affiliation | Department of Endocrinological and Metabolic Sciences, University of Genova, Genova, Italy. | lld:pubmed |
| pubmed-article:16117816 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16117816 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:16117816 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
