| pubmed-article:16107853 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16107853 | lifeskim:mentions | umls-concept:C0038250 | lld:lifeskim |
| pubmed-article:16107853 | lifeskim:mentions | umls-concept:C1182702 | lld:lifeskim |
| pubmed-article:16107853 | lifeskim:mentions | umls-concept:C0015127 | lld:lifeskim |
| pubmed-article:16107853 | lifeskim:mentions | umls-concept:C0087071 | lld:lifeskim |
| pubmed-article:16107853 | lifeskim:mentions | umls-concept:C1314792 | lld:lifeskim |
| pubmed-article:16107853 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:16107853 | lifeskim:mentions | umls-concept:C1701901 | lld:lifeskim |
| pubmed-article:16107853 | lifeskim:mentions | umls-concept:C1514485 | lld:lifeskim |
| pubmed-article:16107853 | pubmed:issue | 7053 | lld:pubmed |
| pubmed-article:16107853 | pubmed:dateCreated | 2005-8-18 | lld:pubmed |
| pubmed-article:16107853 | pubmed:abstractText | TERT, the protein component of telomerase, serves to maintain telomere function through the de novo addition of telomere repeats to chromosome ends, and is reactivated in 90% of human cancers. In normal tissues, TERT is expressed in stem cells and in progenitor cells, but its role in these compartments is not fully understood. Here we show that conditional transgenic induction of TERT in mouse skin epithelium causes a rapid transition from telogen (the resting phase of the hair follicle cycle) to anagen (the active phase), thereby facilitating robust hair growth. TERT overexpression promotes this developmental transition by causing proliferation of quiescent, multipotent stem cells in the hair follicle bulge region. This new function for TERT does not require the telomerase RNA component, which encodes the template for telomere addition, and therefore operates through a mechanism independent of its activity in synthesizing telomere repeats. These data indicate that, in addition to its established role in extending telomeres, TERT can promote proliferation of resting stem cells through a non-canonical pathway. | lld:pubmed |
| pubmed-article:16107853 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16107853 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16107853 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107853 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16107853 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:16107853 | pubmed:issn | 1476-4687 | lld:pubmed |
| pubmed-article:16107853 | pubmed:author | pubmed-author:ArtandiSteven... | lld:pubmed |
| pubmed-article:16107853 | pubmed:author | pubmed-author:OroAnthony... | lld:pubmed |
| pubmed-article:16107853 | pubmed:author | pubmed-author:WangEsteeE | lld:pubmed |
| pubmed-article:16107853 | pubmed:author | pubmed-author:SarinKavita... | lld:pubmed |
| pubmed-article:16107853 | pubmed:author | pubmed-author:CheungPeggieP | lld:pubmed |
| pubmed-article:16107853 | pubmed:author | pubmed-author:GilisonDaniel... | lld:pubmed |
| pubmed-article:16107853 | pubmed:author | pubmed-author:LeeEuniceE | lld:pubmed |
| pubmed-article:16107853 | pubmed:author | pubmed-author:TennenRuth... | lld:pubmed |
| pubmed-article:16107853 | pubmed:author | pubmed-author:ArtandiMaja... | lld:pubmed |
| pubmed-article:16107853 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:16107853 | pubmed:day | 18 | lld:pubmed |
| pubmed-article:16107853 | pubmed:volume | 436 | lld:pubmed |
| pubmed-article:16107853 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16107853 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16107853 | pubmed:pagination | 1048-52 | lld:pubmed |
| pubmed-article:16107853 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:16107853 | pubmed:meshHeading | pubmed-meshheading:16107853... | lld:pubmed |
| pubmed-article:16107853 | pubmed:meshHeading | pubmed-meshheading:16107853... | lld:pubmed |
| pubmed-article:16107853 | pubmed:meshHeading | pubmed-meshheading:16107853... | lld:pubmed |
| pubmed-article:16107853 | pubmed:meshHeading | pubmed-meshheading:16107853... | lld:pubmed |
| pubmed-article:16107853 | pubmed:meshHeading | pubmed-meshheading:16107853... | lld:pubmed |
| pubmed-article:16107853 | pubmed:meshHeading | pubmed-meshheading:16107853... | lld:pubmed |
| pubmed-article:16107853 | pubmed:meshHeading | pubmed-meshheading:16107853... | lld:pubmed |
| pubmed-article:16107853 | pubmed:meshHeading | pubmed-meshheading:16107853... | lld:pubmed |
| pubmed-article:16107853 | pubmed:meshHeading | pubmed-meshheading:16107853... | lld:pubmed |
| pubmed-article:16107853 | pubmed:meshHeading | pubmed-meshheading:16107853... | lld:pubmed |
| pubmed-article:16107853 | pubmed:meshHeading | pubmed-meshheading:16107853... | lld:pubmed |
| pubmed-article:16107853 | pubmed:meshHeading | pubmed-meshheading:16107853... | lld:pubmed |
| pubmed-article:16107853 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:16107853 | pubmed:articleTitle | Conditional telomerase induction causes proliferation of hair follicle stem cells. | lld:pubmed |
| pubmed-article:16107853 | pubmed:affiliation | Department of Medicine, Division of Hematology, Stanford School of Medicine, Stanford, California 94305, USA. | lld:pubmed |
| pubmed-article:16107853 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16107853 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:16107853 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:16107853 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:16107853 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
| entrez-gene:21748 | entrezgene:pubmed | pubmed-article:16107853 | lld:entrezgene |
| entrez-gene:21752 | entrezgene:pubmed | pubmed-article:16107853 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16107853 | lld:pubmed |
