| pubmed-article:16107162 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16107162 | lifeskim:mentions | umls-concept:C0066908 | lld:lifeskim |
| pubmed-article:16107162 | lifeskim:mentions | umls-concept:C1883695 | lld:lifeskim |
| pubmed-article:16107162 | lifeskim:mentions | umls-concept:C0231491 | lld:lifeskim |
| pubmed-article:16107162 | lifeskim:mentions | umls-concept:C1705241 | lld:lifeskim |
| pubmed-article:16107162 | lifeskim:mentions | umls-concept:C0439097 | lld:lifeskim |
| pubmed-article:16107162 | lifeskim:mentions | umls-concept:C1547348 | lld:lifeskim |
| pubmed-article:16107162 | pubmed:issue | 17 | lld:pubmed |
| pubmed-article:16107162 | pubmed:dateCreated | 2005-8-18 | lld:pubmed |
| pubmed-article:16107162 | pubmed:abstractText | H-Dmt-d-Arg-Phe-Lys-NH(2) ([Dmt(1)]DALDA) binds with high affinity and selectivity to the mu opioid receptor and is a potent and long-acting analgesic. Substitution of d-Arg in position 2 with Tic and masking of the lysine amine side chain by Z protection and of the C-terminal carboxylic function instead of the amide function transform a potent and selective mu agonist into a potent and selective delta antagonist H-Dmt-Tic-Phe-Lys(Z)-OH. Such a delta antagonist could be used as a pharmacological tool. | lld:pubmed |
| pubmed-article:16107162 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16107162 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107162 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16107162 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107162 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107162 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107162 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16107162 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16107162 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:16107162 | pubmed:issn | 0022-2623 | lld:pubmed |
| pubmed-article:16107162 | pubmed:author | pubmed-author:RomagnoliRome... | lld:pubmed |
| pubmed-article:16107162 | pubmed:author | pubmed-author:BalboniGianfr... | lld:pubmed |
| pubmed-article:16107162 | pubmed:author | pubmed-author:SalvadoriSeve... | lld:pubmed |
| pubmed-article:16107162 | pubmed:author | pubmed-author:BryantSharon... | lld:pubmed |
| pubmed-article:16107162 | pubmed:author | pubmed-author:LazarusLawren... | lld:pubmed |
| pubmed-article:16107162 | pubmed:author | pubmed-author:CoccoMaria... | lld:pubmed |
| pubmed-article:16107162 | pubmed:author | pubmed-author:SasakiYusukeY | lld:pubmed |
| pubmed-article:16107162 | pubmed:author | pubmed-author:OkadaYoshioY | lld:pubmed |
| pubmed-article:16107162 | pubmed:author | pubmed-author:JinsmaaYunden... | lld:pubmed |
| pubmed-article:16107162 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16107162 | pubmed:day | 25 | lld:pubmed |
| pubmed-article:16107162 | pubmed:volume | 48 | lld:pubmed |
| pubmed-article:16107162 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16107162 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16107162 | pubmed:pagination | 5608-11 | lld:pubmed |
| pubmed-article:16107162 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:16107162 | pubmed:meshHeading | pubmed-meshheading:16107162... | lld:pubmed |
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| pubmed-article:16107162 | pubmed:meshHeading | pubmed-meshheading:16107162... | lld:pubmed |
| pubmed-article:16107162 | pubmed:meshHeading | pubmed-meshheading:16107162... | lld:pubmed |
| pubmed-article:16107162 | pubmed:meshHeading | pubmed-meshheading:16107162... | lld:pubmed |
| pubmed-article:16107162 | pubmed:meshHeading | pubmed-meshheading:16107162... | lld:pubmed |
| pubmed-article:16107162 | pubmed:meshHeading | pubmed-meshheading:16107162... | lld:pubmed |
| pubmed-article:16107162 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:16107162 | pubmed:articleTitle | From the potent and selective mu opioid receptor agonist H-Dmt-d-Arg-Phe-Lys-NH(2) to the potent delta antagonist H-Dmt-Tic-Phe-Lys(Z)-OH. | lld:pubmed |
| pubmed-article:16107162 | pubmed:affiliation | Department of Toxicology, University of Cagliari, I-09124, Cagliari, Italy. gbalboni@unica.it | lld:pubmed |
| pubmed-article:16107162 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16107162 | pubmed:publicationType | In Vitro | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:16107162 | lld:chembl |
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