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pubmed-article:16106306pubmed:abstractTextThe synthesis of a novel spiro[1-benzofuran-2,4'-piperidin]-3-one scaffold has been achieved in five steps with an overall yield of 47%. The versatility of the spiropiperidine scaffold in the context of library synthesis is exemplified by selective and sequential derivatisation of the amino and aryl bromide functional groups, including the development of multi-step telescope reaction matrices.lld:pubmed
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pubmed-article:16106306pubmed:articleTitleSynthesis and derivatisation of a novel spiro[1-benzofuran-2,4'-piperidin]-3-one scaffold.lld:pubmed
pubmed-article:16106306pubmed:affiliationSchool of Chemistry, University of Southampton, Southampton, Hants SO17 1BJ, UK.lld:pubmed
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