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pubmed-article:16095837pubmed:issue1-4lld:pubmed
pubmed-article:16095837pubmed:dateCreated2005-10-31lld:pubmed
pubmed-article:16095837pubmed:abstractTextThe adsorption of plasma protein fibrinogen on the self-assembled monolayers (SAMs) of n-hexadecyl mercaptan and citrate was investigated with atomic force microscopy (AFM). On the basis of the preparation of these two flat SAMs on Au(111), high-resolution AFM images of bovine fibrinogen were obtained with different protein concentrations. The results indicated that the surface chemical composition significantly affected the adsorption behavior of fibrinogen. Since fibrinogen plays a key role in the regulation of both haemostasis and thrombosis, high-resolution AFM imaging on SAMs is expected to be an effective approach to study the haemocompatibility of materials with different surface chemistry.lld:pubmed
pubmed-article:16095837pubmed:languageenglld:pubmed
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pubmed-article:16095837pubmed:statusMEDLINElld:pubmed
pubmed-article:16095837pubmed:monthNovlld:pubmed
pubmed-article:16095837pubmed:issn0304-3991lld:pubmed
pubmed-article:16095837pubmed:authorpubmed-author:ItôHHlld:pubmed
pubmed-article:16095837pubmed:authorpubmed-author:WangJunJlld:pubmed
pubmed-article:16095837pubmed:authorpubmed-author:WanLi-JunLJlld:pubmed
pubmed-article:16095837pubmed:authorpubmed-author:FangXiao-Hong...lld:pubmed
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pubmed-article:16095837pubmed:volume105lld:pubmed
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pubmed-article:16095837pubmed:pagination129-36lld:pubmed
pubmed-article:16095837pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:16095837pubmed:year2005lld:pubmed
pubmed-article:16095837pubmed:articleTitleStudy of fibrinogen adsorption on self-assembled monolayers on Au(111) by atomic force microscopy.lld:pubmed
pubmed-article:16095837pubmed:affiliationCenter of Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China.lld:pubmed
pubmed-article:16095837pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:16095837pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed