| pubmed-article:16080601 | pubmed:abstractText | Elimination of the heat-sensitive l(2)M167(DTS) mutation from artificial Drosophila melanogaster populations at constant temperature 25 degrees C and various frequencies of the mutation in the parental generation was studied. Components of fitness of the l(2)M167(DTS) mutation were estimated in the artificial populations by means of the recurrent model of the dependence of the frequency of this mutation in a given generation on its frequency in the previous generation. The model was solved by a numerical method with limitations on the values of some fitness components obtained in test experiments. According to the limitations and frequencies of the l(2)M167(DTS) mutation, the leading role and limits of the variation in egg-to-adult viability and female fertility were determined. The previously suggested effect of the positive selection for viability of individuals heterozygous for l(2)M167(DTS) was confirmed. | lld:pubmed |
