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pubmed-article:16041064pubmed:abstractTextActivated myofibroblast-like cells, originating from hepatic stellate cells (HSC/MFs) or other cellular sources, play a key profibrogenic role in chronic liver diseases (CLDs) that, as suggested by studies in animal models or rat HSC/MFs, may be modulated by reactive oxygen intermediates (ROI). In this study, human HSC/MFs, exposed to different levels of superoxide anion (O(2)(.-)) and, for comparison, hydrogen peroxide (H(2)O(2)), were analysed in terms of cytotoxicity, proliferative response, and migration.lld:pubmed
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pubmed-article:16041064pubmed:articleTitleDose dependent and divergent effects of superoxide anion on cell death, proliferation, and migration of activated human hepatic stellate cells.lld:pubmed
pubmed-article:16041064pubmed:affiliationUniversità degli Studi di Torino, Dip Medicina e Oncologia Sperimentale, C so Raffaello 30, 10125 Torino, Italy.lld:pubmed
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