| pubmed-article:16023351 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16023351 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:16023351 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:16023351 | lifeskim:mentions | umls-concept:C0037633 | lld:lifeskim |
| pubmed-article:16023351 | lifeskim:mentions | umls-concept:C0678594 | lld:lifeskim |
| pubmed-article:16023351 | lifeskim:mentions | umls-concept:C1382100 | lld:lifeskim |
| pubmed-article:16023351 | lifeskim:mentions | umls-concept:C0243071 | lld:lifeskim |
| pubmed-article:16023351 | lifeskim:mentions | umls-concept:C0205296 | lld:lifeskim |
| pubmed-article:16023351 | lifeskim:mentions | umls-concept:C0165117 | lld:lifeskim |
| pubmed-article:16023351 | lifeskim:mentions | umls-concept:C1449714 | lld:lifeskim |
| pubmed-article:16023351 | pubmed:issue | 17 | lld:pubmed |
| pubmed-article:16023351 | pubmed:dateCreated | 2005-7-29 | lld:pubmed |
| pubmed-article:16023351 | pubmed:abstractText | Recently, we described the synthesis and the biological evaluation of three modified analogues of jaspamide (1), a natural cyclodepsipeptide possessing a potent antitumor activity as a consequence of its ability to interfere with actin cytoskeleton. To obtain additional information on the potential pharmacophoric core of the target molecule, which is of fundamental importance to discover new and more effective anticancer products, we decided to explore the biological effects of further structural modifications carried out on the parent molecule. The synthesis and the chemical characterization of six jaspamide analogues (2-7) are reported and their conformational and biological properties are described. | lld:pubmed |
| pubmed-article:16023351 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16023351 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16023351 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16023351 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16023351 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16023351 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16023351 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16023351 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16023351 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:16023351 | pubmed:issn | 0968-0896 | lld:pubmed |
| pubmed-article:16023351 | pubmed:author | pubmed-author:SmithCharles... | lld:pubmed |
| pubmed-article:16023351 | pubmed:author | pubmed-author:BifulcoGiusep... | lld:pubmed |
| pubmed-article:16023351 | pubmed:author | pubmed-author:Gomez-PalomaL... | lld:pubmed |
| pubmed-article:16023351 | pubmed:author | pubmed-author:RiccioRaffael... | lld:pubmed |
| pubmed-article:16023351 | pubmed:author | pubmed-author:BrunoInesI | lld:pubmed |
| pubmed-article:16023351 | pubmed:author | pubmed-author:TerraccianoSt... | lld:pubmed |
| pubmed-article:16023351 | pubmed:author | pubmed-author:AvalloneElvir... | lld:pubmed |
| pubmed-article:16023351 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16023351 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:16023351 | pubmed:volume | 13 | lld:pubmed |
| pubmed-article:16023351 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16023351 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16023351 | pubmed:pagination | 5225-39 | lld:pubmed |
| pubmed-article:16023351 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:16023351 | pubmed:meshHeading | pubmed-meshheading:16023351... | lld:pubmed |
| pubmed-article:16023351 | pubmed:meshHeading | pubmed-meshheading:16023351... | lld:pubmed |
| pubmed-article:16023351 | pubmed:meshHeading | pubmed-meshheading:16023351... | lld:pubmed |
| pubmed-article:16023351 | pubmed:meshHeading | pubmed-meshheading:16023351... | lld:pubmed |
| pubmed-article:16023351 | pubmed:meshHeading | pubmed-meshheading:16023351... | lld:pubmed |
| pubmed-article:16023351 | pubmed:meshHeading | pubmed-meshheading:16023351... | lld:pubmed |
| pubmed-article:16023351 | pubmed:meshHeading | pubmed-meshheading:16023351... | lld:pubmed |
| pubmed-article:16023351 | pubmed:meshHeading | pubmed-meshheading:16023351... | lld:pubmed |
| pubmed-article:16023351 | pubmed:meshHeading | pubmed-meshheading:16023351... | lld:pubmed |
| pubmed-article:16023351 | pubmed:meshHeading | pubmed-meshheading:16023351... | lld:pubmed |
| pubmed-article:16023351 | pubmed:meshHeading | pubmed-meshheading:16023351... | lld:pubmed |
| pubmed-article:16023351 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:16023351 | pubmed:articleTitle | Synthesis, solution structure, and bioactivity of six new simplified analogues of the natural cyclodepsipeptide jaspamide. | lld:pubmed |
| pubmed-article:16023351 | pubmed:affiliation | Dipartimento di Scienze Farmaceutiche, Università degli Studi di Salerno, via Ponte Don Melillo, 84084 Fisciano (SA), Italy. | lld:pubmed |
| pubmed-article:16023351 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16023351 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16023351 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16023351 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16023351 | lld:pubmed |
