| pubmed-article:16009429 | rdf:type | pubmed:Citation | lld:pubmed |
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| pubmed-article:16009429 | lifeskim:mentions | umls-concept:C0012403 | lld:lifeskim |
| pubmed-article:16009429 | lifeskim:mentions | umls-concept:C0032520 | lld:lifeskim |
| pubmed-article:16009429 | lifeskim:mentions | umls-concept:C0036576 | lld:lifeskim |
| pubmed-article:16009429 | lifeskim:mentions | umls-concept:C0872147 | lld:lifeskim |
| pubmed-article:16009429 | lifeskim:mentions | umls-concept:C1519249 | lld:lifeskim |
| pubmed-article:16009429 | lifeskim:mentions | umls-concept:C0439605 | lld:lifeskim |
| pubmed-article:16009429 | lifeskim:mentions | umls-concept:C1533691 | lld:lifeskim |
| pubmed-article:16009429 | lifeskim:mentions | umls-concept:C0185125 | lld:lifeskim |
| pubmed-article:16009429 | lifeskim:mentions | umls-concept:C1521871 | lld:lifeskim |
| pubmed-article:16009429 | lifeskim:mentions | umls-concept:C2349975 | lld:lifeskim |
| pubmed-article:16009429 | lifeskim:mentions | umls-concept:C0599013 | lld:lifeskim |
| pubmed-article:16009429 | lifeskim:mentions | umls-concept:C1627358 | lld:lifeskim |
| pubmed-article:16009429 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:16009429 | pubmed:dateCreated | 2005-8-22 | lld:pubmed |
| pubmed-article:16009429 | pubmed:abstractText | A PCR method for uniform amplification of a random sequence DNA library is described. A combination of 1 M betaine and 5% DMSO improves the PCR amplification by increasing the ratio of full-length products to shortened products, which are a consequence of nonuniform amplification due to stable secondary structures in the templates. This method is expected to be beneficial for obtaining high-affinity aptamers with stable secondary structures. | lld:pubmed |
| pubmed-article:16009429 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16009429 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16009429 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16009429 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16009429 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16009429 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16009429 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16009429 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:16009429 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16009429 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16009429 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:16009429 | pubmed:issn | 0165-022X | lld:pubmed |
| pubmed-article:16009429 | pubmed:author | pubmed-author:GorensteinDav... | lld:pubmed |
| pubmed-article:16009429 | pubmed:author | pubmed-author:LeeMyung... | lld:pubmed |
| pubmed-article:16009429 | pubmed:author | pubmed-author:KangJonghoonJ | lld:pubmed |
| pubmed-article:16009429 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16009429 | pubmed:day | 31 | lld:pubmed |
| pubmed-article:16009429 | pubmed:volume | 64 | lld:pubmed |
| pubmed-article:16009429 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16009429 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16009429 | pubmed:pagination | 147-51 | lld:pubmed |
| pubmed-article:16009429 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:16009429 | pubmed:meshHeading | pubmed-meshheading:16009429... | lld:pubmed |
| pubmed-article:16009429 | pubmed:meshHeading | pubmed-meshheading:16009429... | lld:pubmed |
| pubmed-article:16009429 | pubmed:meshHeading | pubmed-meshheading:16009429... | lld:pubmed |
| pubmed-article:16009429 | pubmed:meshHeading | pubmed-meshheading:16009429... | lld:pubmed |
| pubmed-article:16009429 | pubmed:meshHeading | pubmed-meshheading:16009429... | lld:pubmed |
| pubmed-article:16009429 | pubmed:meshHeading | pubmed-meshheading:16009429... | lld:pubmed |
| pubmed-article:16009429 | pubmed:meshHeading | pubmed-meshheading:16009429... | lld:pubmed |
| pubmed-article:16009429 | pubmed:meshHeading | pubmed-meshheading:16009429... | lld:pubmed |
| pubmed-article:16009429 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:16009429 | pubmed:articleTitle | The enhancement of PCR amplification of a random sequence DNA library by DMSO and betaine: application to in vitro combinatorial selection of aptamers. | lld:pubmed |
| pubmed-article:16009429 | pubmed:affiliation | Department of Human Biological Chemistry and Genetics, Sealy Center for Structural Biology, The University of Texas Medical Branch, Galveston, TX 77555-1157, USA. | lld:pubmed |
| pubmed-article:16009429 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16009429 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:16009429 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:16009429 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| pubmed-article:16009429 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
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