| pubmed-article:16005170 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16005170 | lifeskim:mentions | umls-concept:C0031336 | lld:lifeskim |
| pubmed-article:16005170 | lifeskim:mentions | umls-concept:C1524059 | lld:lifeskim |
| pubmed-article:16005170 | lifeskim:mentions | umls-concept:C0031327 | lld:lifeskim |
| pubmed-article:16005170 | lifeskim:mentions | umls-concept:C0013058 | lld:lifeskim |
| pubmed-article:16005170 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:16005170 | lifeskim:mentions | umls-concept:C0205360 | lld:lifeskim |
| pubmed-article:16005170 | lifeskim:mentions | umls-concept:C0311404 | lld:lifeskim |
| pubmed-article:16005170 | lifeskim:mentions | umls-concept:C1148564 | lld:lifeskim |
| pubmed-article:16005170 | lifeskim:mentions | umls-concept:C0028908 | lld:lifeskim |
| pubmed-article:16005170 | lifeskim:mentions | umls-concept:C1553890 | lld:lifeskim |
| pubmed-article:16005170 | lifeskim:mentions | umls-concept:C0061081 | lld:lifeskim |
| pubmed-article:16005170 | pubmed:issue | 1-2 | lld:pubmed |
| pubmed-article:16005170 | pubmed:dateCreated | 2005-7-18 | lld:pubmed |
| pubmed-article:16005170 | pubmed:abstractText | Gamma-oryzanol, a phytosteryl ferulate mixture extracted from rice bran oil, has a wide spectrum of biological activities; in particular, it has antioxidant properties and is often used in cosmetic formulations as a sunscreen. The first objective of the present investigation was to elucidate the molecular mechanism(s) of the antioxidant activity of gamma-oryzanol by utilising different in vitro model systems, such as scavenging of stable DPPH radical, OH and O2- radicals scavenging, and azocompound AMVN-initiated lipid peroxidation. The effect of gamma-oryzanol on the oxidative stability of vegetable oils of pharmaceutical and cosmetic interest was then evaluated in a oxidation accelerate test and compared with the effect of the well-known antioxidants BHA and BHT. Our results demonstrate that gamma-oryzanol is an organic radical scavenger able to prevent AMVN-triggered lipoperoxidation. Moreover, when added to oils at concentrations ranging between 2.5 and 10 mmol/kg, gamma-oryzanol shows a dose-dependent increase of the induction times; in particular, it improved the oxidative stability of oils very prone to lipoperoxidation because of their high content of polyunsaturated fatty acids. On the ground of our results, we can conclude that gamma-oryzanol may have a potential application for the stabilization of lipidic raw materials. | lld:pubmed |
| pubmed-article:16005170 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16005170 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16005170 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16005170 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16005170 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16005170 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16005170 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:16005170 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16005170 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16005170 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16005170 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16005170 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16005170 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16005170 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16005170 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16005170 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16005170 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16005170 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16005170 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:16005170 | pubmed:issn | 0378-5173 | lld:pubmed |
| pubmed-article:16005170 | pubmed:author | pubmed-author:JulianoClaudi... | lld:pubmed |
| pubmed-article:16005170 | pubmed:author | pubmed-author:CossuMassimoM | lld:pubmed |
| pubmed-article:16005170 | pubmed:author | pubmed-author:AlamanniMaria... | lld:pubmed |
| pubmed-article:16005170 | pubmed:author | pubmed-author:PiuLuisellaL | lld:pubmed |
| pubmed-article:16005170 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16005170 | pubmed:day | 11 | lld:pubmed |
| pubmed-article:16005170 | pubmed:volume | 299 | lld:pubmed |
| pubmed-article:16005170 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16005170 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16005170 | pubmed:pagination | 146-54 | lld:pubmed |
| pubmed-article:16005170 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
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| pubmed-article:16005170 | pubmed:meshHeading | pubmed-meshheading:16005170... | lld:pubmed |
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| pubmed-article:16005170 | pubmed:meshHeading | pubmed-meshheading:16005170... | lld:pubmed |
| pubmed-article:16005170 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:16005170 | pubmed:articleTitle | Antioxidant activity of gamma-oryzanol: mechanism of action and its effect on oxidative stability of pharmaceutical oils. | lld:pubmed |
| pubmed-article:16005170 | pubmed:affiliation | Dipartimento di Scienze del Farmaco, Via Muroni 23/A, University of Sassari, Sassari, Italy. julianoc@uniss.it | lld:pubmed |
| pubmed-article:16005170 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16005170 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16005170 | lld:pubmed |
