| pubmed-article:1599953 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1599953 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
| pubmed-article:1599953 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:1599953 | lifeskim:mentions | umls-concept:C0205054 | lld:lifeskim |
| pubmed-article:1599953 | lifeskim:mentions | umls-concept:C0678723 | lld:lifeskim |
| pubmed-article:1599953 | lifeskim:mentions | umls-concept:C0392747 | lld:lifeskim |
| pubmed-article:1599953 | lifeskim:mentions | umls-concept:C0051118 | lld:lifeskim |
| pubmed-article:1599953 | lifeskim:mentions | umls-concept:C0443172 | lld:lifeskim |
| pubmed-article:1599953 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
| pubmed-article:1599953 | lifeskim:mentions | umls-concept:C0458003 | lld:lifeskim |
| pubmed-article:1599953 | pubmed:issue | 1-2 | lld:pubmed |
| pubmed-article:1599953 | pubmed:dateCreated | 1992-7-14 | lld:pubmed |
| pubmed-article:1599953 | pubmed:abstractText | A major isoenzyme of hepatic androsterone-sulfating sulfotransferase (AD-ST) was purified from adult female rats. The activity was purified 122-fold over that found in the cytosol and showed a single protein band with a subunit molecular mass of 30 kDa after sodium dodecyl sulfate polyacrylamide gel electrophoresis. The purified enzyme exhibited four isoelectric variants of subunits on denaturing isoelectrofocusing gels (pI = 5.8, 6.1, 6.7 and 7.2). Rabbit antiserum raised against the enzyme specifically detected AD-ST polypeptide in rat liver cytosol. Immunoblot analysis of liver cytosol from female and male rats at various ages showed good correlation between the levels of AD-ST activity and AD-ST polypeptide. Significant levels of AD-ST activity and polypeptide were detected in senescent male rats, though normal adult male rats have very low levels of AD-ST activity and protein. The relative content of the isoelectric variants of AD-ST were different in liver cytosol of weanling and adult females, indicating that age- and gender-related alterations of hepatic AD-ST activity are primarily determined by the levels of AD-ST polypeptide and the relative amounts of the four isoelectric variants of the enzyme. | lld:pubmed |
| pubmed-article:1599953 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1599953 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1599953 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1599953 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1599953 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1599953 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1599953 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1599953 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1599953 | pubmed:month | May | lld:pubmed |
| pubmed-article:1599953 | pubmed:issn | 0006-3002 | lld:pubmed |
| pubmed-article:1599953 | pubmed:author | pubmed-author:MatsuiMM | lld:pubmed |
| pubmed-article:1599953 | pubmed:author | pubmed-author:KamakuraMM | lld:pubmed |
| pubmed-article:1599953 | pubmed:author | pubmed-author:HommaHH | lld:pubmed |
| pubmed-article:1599953 | pubmed:author | pubmed-author:NakagomiMM | lld:pubmed |
| pubmed-article:1599953 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1599953 | pubmed:day | 22 | lld:pubmed |
| pubmed-article:1599953 | pubmed:volume | 1121 | lld:pubmed |
| pubmed-article:1599953 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1599953 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1599953 | pubmed:pagination | 69-74 | lld:pubmed |
| pubmed-article:1599953 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:1599953 | pubmed:meshHeading | pubmed-meshheading:1599953-... | lld:pubmed |
| pubmed-article:1599953 | pubmed:meshHeading | pubmed-meshheading:1599953-... | lld:pubmed |
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| pubmed-article:1599953 | pubmed:meshHeading | pubmed-meshheading:1599953-... | lld:pubmed |
| pubmed-article:1599953 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1599953 | pubmed:articleTitle | Immunochemical characterization of developmental changes in rat hepatic hydroxysteroid sulfotransferase. | lld:pubmed |
| pubmed-article:1599953 | pubmed:affiliation | Kyoritsu College of Pharmacy, Tokyo, Japan. | lld:pubmed |
| pubmed-article:1599953 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1599953 | pubmed:publicationType | Comparative Study | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:1599953 | lld:pubmed |
