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pubmed-article:15993857pubmed:abstractTextMost patients with obsessive-compulsive disorder (OCD) show only partial reduction of symptoms with standard therapy. Recent imaging data suggests glutamatergic dysfunction in the corticostriatal pathway in OCD. We investigated the efficacy of augmentation therapy with riluzole, a glutamate-modulating agent, in treatment-resistant OCD.lld:pubmed
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pubmed-article:15993857pubmed:articleTitleRiluzole augmentation in treatment-resistant obsessive-compulsive disorder: an open-label trial.lld:pubmed
pubmed-article:15993857pubmed:affiliationDepartment of Psychiatry, Yale University School of Medicine and Connecticut Mental Health Center, 34 Park Street, New Haven, CT 06519, USA. vladimir.coric@yale.edulld:pubmed
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