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pubmed-article:15975223pubmed:abstractTextGene expression can be studied at a genome-wide scale with the aid of modern microarray technologies. Expression profiling of tens to hundreds of individuals in a genetic population can reveal the consequences of genetic variation. In this paper it is argued that the design and analysis of such a study is not a matter of simply applying the existing and more-or-less standard computational tools for microarrays to a new type of experimental data. It is shown how to fully exploit the power of genetics through optimal experimental design and analysis for two major microarray technologies, cDNA two-colour arrays and Affymetrix short oligonucleotide arrays.lld:pubmed
pubmed-article:15975223pubmed:languageenglld:pubmed
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pubmed-article:15975223pubmed:pagination135-45lld:pubmed
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pubmed-article:15975223pubmed:year2005lld:pubmed
pubmed-article:15975223pubmed:articleTitleCombining microarrays and genetic analysis.lld:pubmed
pubmed-article:15975223pubmed:affiliationGroningen Bioinformatics Centre, University of Groningen, Kerklaan 30, 9751 NN, Haren, the Netherlands.lld:pubmed
pubmed-article:15975223pubmed:publicationTypeJournal Articlelld:pubmed
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