| pubmed-article:15973150 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15973150 | lifeskim:mentions | umls-concept:C0027882 | lld:lifeskim |
| pubmed-article:15973150 | lifeskim:mentions | umls-concept:C0020663 | lld:lifeskim |
| pubmed-article:15973150 | lifeskim:mentions | umls-concept:C2587213 | lld:lifeskim |
| pubmed-article:15973150 | lifeskim:mentions | umls-concept:C1511572 | lld:lifeskim |
| pubmed-article:15973150 | pubmed:issue | 10 | lld:pubmed |
| pubmed-article:15973150 | pubmed:dateCreated | 2005-6-23 | lld:pubmed |
| pubmed-article:15973150 | pubmed:abstractText | The perifornical-lateral hypothalamic area is implicated in regulating waking and paradoxical sleep. The blockade of GABAA receptors by iontophoretic applications of bicuculline (or gabazine) into the perifornical-lateral hypothalamic area induced a continuous quiet waking state associated to a robust muscle tone in head-restrained rats. During the effects, sleep was totally suppressed. In rats killed at the end of a 90 min ejection of bicuculline, Fos expression was induced in approximately 28% of the neurons immunoreactive for hypocretin and in approximately 3% of the neurons immunostained for melanin-concentrating hormone within the ejection site. These results suggest that neurons containing melanin-concentrating hormone are not active during waking and that the lack of a potent GABAergic influence during waking is consistent with their role in sleep regulation. | lld:pubmed |
| pubmed-article:15973150 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15973150 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15973150 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:15973150 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15973150 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:15973150 | pubmed:issn | 0959-4965 | lld:pubmed |
| pubmed-article:15973150 | pubmed:author | pubmed-author:GervasoniDami... | lld:pubmed |
| pubmed-article:15973150 | pubmed:author | pubmed-author:FortPatriceP | lld:pubmed |
| pubmed-article:15973150 | pubmed:author | pubmed-author:LuppiPierre-H... | lld:pubmed |
| pubmed-article:15973150 | pubmed:author | pubmed-author:GoutagnyRomai... | lld:pubmed |
| pubmed-article:15973150 | pubmed:author | pubmed-author:SalvertDenise... | lld:pubmed |
| pubmed-article:15973150 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15973150 | pubmed:day | 13 | lld:pubmed |
| pubmed-article:15973150 | pubmed:volume | 16 | lld:pubmed |
| pubmed-article:15973150 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15973150 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15973150 | pubmed:pagination | 1069-73 | lld:pubmed |
| pubmed-article:15973150 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
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| pubmed-article:15973150 | pubmed:meshHeading | pubmed-meshheading:15973150... | lld:pubmed |
| pubmed-article:15973150 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:15973150 | pubmed:articleTitle | GABAergic control of hypothalamic melanin-concentrating hormone-containing neurons across the sleep-waking cycle. | lld:pubmed |
| pubmed-article:15973150 | pubmed:affiliation | CNRS, UMR 5167, Faculté de Medecine, RTH Laennec, 7 rue G. Paradin, 69372 Lyon cedex 08, France. | lld:pubmed |
| pubmed-article:15973150 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15973150 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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