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pubmed-article:15972567pubmed:abstractTextIn the United States, an estimated 2 million persons have neuropathic pain that is often resistant to therapy. The use of opioids for neuropathic pain remains controversial, in part because studies have been small, have yielded equivocal results, and have not established the long-term risk-benefit ratio of this treatment.lld:pubmed
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pubmed-article:15972567pubmed:articleTitleEfficacy and safety of opioid agonists in the treatment of neuropathic pain of nonmalignant origin: systematic review and meta-analysis of randomized controlled trials.lld:pubmed
pubmed-article:15972567pubmed:affiliationPain Relief Unit, Rambam Medical Center, and Haifa Pain Research Group, the Technion-Israel Institute of Technology, Haifa, Israel. e_eisenberg@rambam.health.gov.illld:pubmed
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