Linked Life Data

15958294

Source:http://linkedlifedata.com/resource/pubmed/id/15958294

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SubjectPredicateObjectContext
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pubmed-article:15958294pubmed:issue6lld:pubmed
pubmed-article:15958294pubmed:dateCreated2005-6-16lld:pubmed
pubmed-article:15958294pubmed:abstractTextMagnetic fluid containing Fe(3)O(4) as mother nucleus was prepared by chemical coprecipitation and treated with dextran-70 for surface modification. The dextran-70-modified magnetic fluid was reacted with 6-bromohexanoic acid and their chemical stability was studied, with the structure characterized by using laser granulometer, X-ray diffraction, Fourier-transform infrared analysis and transmission electron microscopy. The results showed that the magnetic fluid with surface modification by dextran-70 exhibited high stability in the presence strong alkali or acid. No chemical changes occurred in the magnetic Fe(3)O(4) nucleus surrounded by alkali-treated dextran-70 and the organic chain linked to the surface dextran rendered the reaction to the anti-cancer drug such as mitomycin C possible, suggesting the potential of the preparation as a drug carrier.lld:pubmed
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pubmed-article:15958294pubmed:authorpubmed-author:TewW MWMlld:pubmed
pubmed-article:15958294pubmed:authorpubmed-author:TomP APAlld:pubmed
pubmed-article:15958294pubmed:authorpubmed-author:ChenJian-haiJ...lld:pubmed
pubmed-article:15958294pubmed:authorpubmed-author:YanXi-qingXQlld:pubmed
pubmed-article:15958294pubmed:authorpubmed-author:JiangQing-fen...lld:pubmed
pubmed-article:15958294pubmed:authorpubmed-author:WuZhi-shenZSlld:pubmed
pubmed-article:15958294pubmed:issnTypePrintlld:pubmed
pubmed-article:15958294pubmed:volume25lld:pubmed
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pubmed-article:15958294pubmed:pagination626-9lld:pubmed
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pubmed-article:15958294pubmed:year2005lld:pubmed
pubmed-article:15958294pubmed:articleTitle[Preparation and surface modification of the magnetic fluid as a targeted drug carrier].lld:pubmed
pubmed-article:15958294pubmed:affiliationDepartment of Pharmacy, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. yxqdoctor@163.comlld:pubmed
pubmed-article:15958294pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:15958294pubmed:publicationTypeEnglish Abstractlld:pubmed
pubmed-article:15958294pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed