| pubmed-article:15939047 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15939047 | lifeskim:mentions | umls-concept:C0001390 | lld:lifeskim |
| pubmed-article:15939047 | lifeskim:mentions | umls-concept:C0031617 | lld:lifeskim |
| pubmed-article:15939047 | lifeskim:mentions | umls-concept:C0042839 | lld:lifeskim |
| pubmed-article:15939047 | lifeskim:mentions | umls-concept:C0087161 | lld:lifeskim |
| pubmed-article:15939047 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:15939047 | pubmed:dateCreated | 2005-6-7 | lld:pubmed |
| pubmed-article:15939047 | pubmed:abstractText | The purpose of this study is to investigate if a readily available cell line (APRE-19) may be used to study in vitro function of visual cycle enzymes such as lecithin:retinol acyltransferase (LRAT). Cells incubated with exogenous retinol accumulated intracellular all-trans retinol and all-trans retinyl ester. Membrane proteins from ARPE-19 exhibited LRAT activity, which was inhibited by an LRAT inhibitor, retinyl bromoacetate (RBA). Gene microarray and Western blot results indicated that ARPE-19 cells expressed LRAT transcript and the LRAT protein. Therefore, our data show that ARPE-19 contains an active LRAT enzyme and suggest that it is an appropriate cell system to study visual cycle enzymes. | lld:pubmed |
| pubmed-article:15939047 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15939047 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15939047 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15939047 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15939047 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15939047 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15939047 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15939047 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15939047 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15939047 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15939047 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15939047 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:15939047 | pubmed:issn | 0014-4835 | lld:pubmed |
| pubmed-article:15939047 | pubmed:author | pubmed-author:BowmanPhillip... | lld:pubmed |
| pubmed-article:15939047 | pubmed:author | pubmed-author:SchuscherebaS... | lld:pubmed |
| pubmed-article:15939047 | pubmed:author | pubmed-author:TrevinoSimon... | lld:pubmed |
| pubmed-article:15939047 | pubmed:author | pubmed-author:TsinAndrewA | lld:pubmed |
| pubmed-article:15939047 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15939047 | pubmed:volume | 80 | lld:pubmed |
| pubmed-article:15939047 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15939047 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15939047 | pubmed:pagination | 897-900 | lld:pubmed |
| pubmed-article:15939047 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:15939047 | pubmed:meshHeading | pubmed-meshheading:15939047... | lld:pubmed |
| pubmed-article:15939047 | pubmed:meshHeading | pubmed-meshheading:15939047... | lld:pubmed |
| pubmed-article:15939047 | pubmed:meshHeading | pubmed-meshheading:15939047... | lld:pubmed |
| pubmed-article:15939047 | pubmed:meshHeading | pubmed-meshheading:15939047... | lld:pubmed |
| pubmed-article:15939047 | pubmed:meshHeading | pubmed-meshheading:15939047... | lld:pubmed |
| pubmed-article:15939047 | pubmed:meshHeading | pubmed-meshheading:15939047... | lld:pubmed |
| pubmed-article:15939047 | pubmed:meshHeading | pubmed-meshheading:15939047... | lld:pubmed |
| pubmed-article:15939047 | pubmed:meshHeading | pubmed-meshheading:15939047... | lld:pubmed |
| pubmed-article:15939047 | pubmed:meshHeading | pubmed-meshheading:15939047... | lld:pubmed |
| pubmed-article:15939047 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:15939047 | pubmed:articleTitle | Lecithin:retinol acyltransferase in ARPE-19. | lld:pubmed |
| pubmed-article:15939047 | pubmed:affiliation | Department of Biology, the University of Texas at San Antonio, San Antonio, TX 78249, USA. | lld:pubmed |
| pubmed-article:15939047 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15939047 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:15939047 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
