pubmed-article:1592713 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:1592713 | lifeskim:mentions | umls-concept:C0024109 | lld:lifeskim |
pubmed-article:1592713 | lifeskim:mentions | umls-concept:C0034493 | lld:lifeskim |
pubmed-article:1592713 | lifeskim:mentions | umls-concept:C0596790 | lld:lifeskim |
pubmed-article:1592713 | lifeskim:mentions | umls-concept:C1550244 | lld:lifeskim |
pubmed-article:1592713 | lifeskim:mentions | umls-concept:C0020197 | lld:lifeskim |
pubmed-article:1592713 | lifeskim:mentions | umls-concept:C0033095 | lld:lifeskim |
pubmed-article:1592713 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
pubmed-article:1592713 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
pubmed-article:1592713 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
pubmed-article:1592713 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
pubmed-article:1592713 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
pubmed-article:1592713 | lifeskim:mentions | umls-concept:C1706501 | lld:lifeskim |
pubmed-article:1592713 | pubmed:issue | 4 | lld:pubmed |
pubmed-article:1592713 | pubmed:dateCreated | 1992-6-29 | lld:pubmed |
pubmed-article:1592713 | pubmed:abstractText | The sequential pattern of perivascular interstitial cuff growth was studied in liquid-inflated rabbit lungs. Degassed isolated lungs were immersed in a saline bath and inflated to 5 cmH2O transpulmonary pressure with a 3% albumin solution or 3% albumin solution containing hyaluronidase. After inflation times varying between 1 and 7 h, the lungs were frozen in liquid N2. From blocks cut from the frozen lungs, interstitial cuff cross-sectional area was measured as a function of vessel size. No cuffs were observed around vessels less than 0.1 mm diam. At all inflation times, only approximately 50% of vessels less than 0.5 mm diam had cuffs, whereas virtually all vessels greater than 0.5 mm diam had cuffs. Cuff-to-vessel area ratio increased with inflation time, reaching a maximum of 1.0-1.4 by 5 h. The time constant of cuff growth was 1 h for the albumin-inflated lungs and was independent of vessel size. The time constant was reduced by 60% in the hyaluronidase-inflated lungs. The time constant for the response in perivascular interstitial pressure measured by micropuncture near the lung hilum was 2.5 h for albumin-inflated lungs and 1.2 h for hyaluronidase-inflated lungs. Electrical analog models were used to fit the experimental data of cuff growth and to determine interstitial liquid resistance. Interstitial resistance for the albumin-inflated rabbit lungs was 2- and 24-fold greater than values estimated previously for sheep and dog lungs, respectively. | lld:pubmed |
pubmed-article:1592713 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1592713 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1592713 | pubmed:language | eng | lld:pubmed |
pubmed-article:1592713 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1592713 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:1592713 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1592713 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:1592713 | pubmed:month | Apr | lld:pubmed |
pubmed-article:1592713 | pubmed:issn | 8750-7587 | lld:pubmed |
pubmed-article:1592713 | pubmed:author | pubmed-author:OOIS KSK | lld:pubmed |
pubmed-article:1592713 | pubmed:author | pubmed-author:Lai-FookS JSJ | lld:pubmed |
pubmed-article:1592713 | pubmed:author | pubmed-author:ConhaimR LRL | lld:pubmed |
pubmed-article:1592713 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:1592713 | pubmed:volume | 72 | lld:pubmed |
pubmed-article:1592713 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:1592713 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:1592713 | pubmed:pagination | 1261-9 | lld:pubmed |
pubmed-article:1592713 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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pubmed-article:1592713 | pubmed:year | 1992 | lld:pubmed |
pubmed-article:1592713 | pubmed:articleTitle | Effect of hyaluronidase on interstitial cuff and pressure response in liquid-inflated rabbit lung. | lld:pubmed |
pubmed-article:1592713 | pubmed:affiliation | Center for Biomedical Engineering, University of Kentucky, Lexington 40506. | lld:pubmed |
pubmed-article:1592713 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:1592713 | pubmed:publicationType | Comparative Study | lld:pubmed |
pubmed-article:1592713 | pubmed:publicationType | In Vitro | lld:pubmed |
pubmed-article:1592713 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |